ENSG00000135625


Homo sapiens

Features
Gene ID: ENSG00000135625
  
Biological name :EGR4
  
Synonyms : early growth response 4 / EGR4 / Q05215
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p13.2
Gene start: 73290929
Gene end: 73293705
  
Corresponding Affymetrix probe sets: 207767_s_at (Human Genome U133 Plus 2.0 Array)   207768_at (Human Genome U133 Plus 2.0 Array)   231575_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419687
Ensembl peptide - ENSP00000445626
NCBI entrez gene - 1961     See in Manteia.
OMIM - 128992
RefSeq - NM_001965
RefSeq Peptide - NP_001956
swissprot - A0A0C4DG96
swissprot - Q05215
Ensembl - ENSG00000135625
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 egr4ENSDARG00000077799Danio rerio
 EGR4ENSGALG00000016086Gallus gallus
 Egr4ENSMUSG00000071341Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EGR2 / P11161 / early growth response 2ENSG0000012287725
EGR1 / P18146 / early growth response 1ENSG0000012073821
EGR3 / Q06889 / early growth response 3ENSG0000017938821
WT1 / P19544 / Wilms tumor 1ENSG0000018493719


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IC
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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