ENSG00000179388


Homo sapiens

Features
Gene ID: ENSG00000179388
  
Biological name :EGR3
  
Synonyms : early growth response 3 / EGR3 / Q06889
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: p21.3
Gene start: 22687659
Gene end: 22693302
  
Corresponding Affymetrix probe sets: 206115_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000430310
Ensembl peptide - ENSP00000318057
Ensembl peptide - ENSP00000429370
NCBI entrez gene - 1960     See in Manteia.
OMIM - 602419
RefSeq - XM_011544429
RefSeq - NM_001199880
RefSeq - NM_004430
RefSeq - XM_005273426
RefSeq Peptide - NP_004421
RefSeq Peptide - NP_001186809
swissprot - Q06889
swissprot - E5RIM5
Ensembl - ENSG00000179388
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 egr3ENSDARG00000089156Danio rerio
 Egr3ENSMUSG00000033730Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EGR2 / P11161 / early growth response 2ENSG0000012287750
EGR1 / P18146 / early growth response 1ENSG0000012073846
EGR4 / Q05215 / early growth response 4ENSG0000013562532
WT1 / P19544 / Wilms tumor 1ENSG0000018493725


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR021849  Early growth response protein
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IMP
 biological_processGO:0002042 cell migration involved in sprouting angiogenesis IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007274 neuromuscular synaptic transmission IEA
 biological_processGO:0007422 peripheral nervous system development IEA
 biological_processGO:0007517 muscle organ development TAS
 biological_processGO:0007623 circadian rhythm TAS
 biological_processGO:0033089 positive regulation of T cell differentiation in thymus IEA
 biological_processGO:0035767 endothelial cell chemotaxis IMP
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IMP
 biological_processGO:0045586 regulation of gamma-delta T cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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