ENSG00000135912


Homo sapiens

Features
Gene ID: ENSG00000135912
  
Biological name :TTLL4
  
Synonyms : Q14679 / TTLL4 / tubulin tyrosine ligase like 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q35
Gene start: 218710845
Gene end: 218755416
  
Corresponding Affymetrix probe sets: 1557611_at (Human Genome U133 Plus 2.0 Array)   203702_s_at (Human Genome U133 Plus 2.0 Array)   203703_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396555
Ensembl peptide - ENSP00000415845
Ensembl peptide - ENSP00000415197
Ensembl peptide - ENSP00000411228
Ensembl peptide - ENSP00000407434
Ensembl peptide - ENSP00000405485
Ensembl peptide - ENSP00000400068
Ensembl peptide - ENSP00000258398
Ensembl peptide - ENSP00000375951
Ensembl peptide - ENSP00000391342
Ensembl peptide - ENSP00000392103
Ensembl peptide - ENSP00000393332
NCBI entrez gene - 9654     See in Manteia.
RefSeq - XM_017005392
RefSeq - NM_014640
RefSeq - XM_006712875
RefSeq - XM_017005387
RefSeq - XM_017005388
RefSeq - XM_017005389
RefSeq - XM_017005390
RefSeq - XM_017005391
RefSeq Peptide - NP_055455
swissprot - H7C421
swissprot - E9PH58
swissprot - Q14679
swissprot - H7C470
swissprot - E7EX20
swissprot - C9JB60
swissprot - C9J982
swissprot - C9J3I1
swissprot - A0A024R424
swissprot - H7BZY4
swissprot - H7C1F7
swissprot - H7C2S3
Ensembl - ENSG00000135912
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttll4ENSDARG00000078935Danio rerio
 TTLL4ENSGALG00000027991Gallus gallus
 Ttll4ENSMUSG00000033257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TTLL5 / Q6EMB2 / tubulin tyrosine ligase like 5ENSG0000011968519
TTLL6 / Q8N841 / tubulin tyrosine ligase like 6ENSG0000017070315
Q8NHH1 / TTLL11 / tubulin tyrosine ligase like 11ENSG0000017576414
TTLL7 / Q6ZT98 / tubulin tyrosine ligase like 7ENSG0000013794113
A6NNM8 / TTLL13P / tubulin tyrosine ligase like 13, pseudogeneENSG0000021347112
TTLL2 / Q9BWV7 / tubulin tyrosine ligase like 2ENSG0000012044012
Q6ZVT0 / TTLL10 / tubulin tyrosine ligase like 10ENSG0000016257110
TTLL9 / Q3SXZ7 / tubulin tyrosine ligase like 9ENSG0000013104410
TTLL3 / Q9Y4R7 / tubulin tyrosine ligase like 3ENSG000002140219
TTLL1 / O95922 / tubulin tyrosine ligase like 1ENSG000001002719
TTLL8 / A6PVC2 / tubulin tyrosine ligase like 8ENSG000001388928
ARPC4-TTLL3 / ARPC4-TTLL3 readthroughENSG000002501517


Protein motifs (from Interpro)
Interpro ID Name
 IPR004344  Tubulin-tyrosine ligase/Tubulin polyglutamylase
 IPR027748  Tubulin polyglutamylase TTLL-4
 IPR027749  Tubulin--tyrosine ligase-like protein 12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0018095 protein polyglutamylation ISS
 biological_processGO:0018200 peptidyl-glutamic acid modification ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015631 tubulin binding ISS
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0070739 protein-glutamic acid ligase activity ISS
 molecular_functionGO:0070740 tubulin-glutamic acid ligase activity TAS


Pathways (from Reactome)
Pathway description
Carboxyterminal post-translational modifications of tubulin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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