ENSG00000170703


Homo sapiens

Features
Gene ID: ENSG00000170703
  
Biological name :TTLL6
  
Synonyms : Q8N841 / TTLL6 / tubulin tyrosine ligase like 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.32
Gene start: 48762235
Gene end: 48817214
  
Corresponding Affymetrix probe sets: 230924_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415138
Ensembl peptide - ENSP00000400624
Ensembl peptide - ENSP00000414290
Ensembl peptide - ENSP00000365871
Ensembl peptide - ENSP00000377043
Ensembl peptide - ENSP00000399211
NCBI entrez gene - 284076     See in Manteia.
OMIM - 610849
RefSeq - XM_017024497
RefSeq - NM_173623
RefSeq - XM_017024491
RefSeq - XM_017024492
RefSeq - XM_017024493
RefSeq - XM_017024494
RefSeq - XM_017024495
RefSeq - XM_017024496
RefSeq - NM_001130918
RefSeq Peptide - NP_001124390
RefSeq Peptide - NP_775894
swissprot - F8WDP8
swissprot - F8W896
swissprot - F6QD81
swissprot - Q8N841
swissprot - F8W9N0
Ensembl - ENSG00000170703
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttll6ENSDARG00000054023Danio rerio
 Ttll6ENSMUSG00000038756Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NNM8 / TTLL13P / tubulin tyrosine ligase like 13, pseudogeneENSG0000021347140
TTLL7 / Q6ZT98 / tubulin tyrosine ligase like 7ENSG0000013794129
TTLL5 / Q6EMB2 / tubulin tyrosine ligase like 5ENSG0000011968523
Q8NHH1 / TTLL11 / tubulin tyrosine ligase like 11ENSG0000017576421
TTLL4 / Q14679 / tubulin tyrosine ligase like 4ENSG0000013591220
TTLL2 / Q9BWV7 / tubulin tyrosine ligase like 2ENSG0000012044016
TTLL1 / O95922 / tubulin tyrosine ligase like 1ENSG0000010027114
TTLL9 / Q3SXZ7 / tubulin tyrosine ligase like 9ENSG0000013104414
TTLL8 / A6PVC2 / tubulin tyrosine ligase like 8ENSG0000013889214
Q6ZVT0 / TTLL10 / tubulin tyrosine ligase like 10ENSG0000016257113
TTLL3 / Q9Y4R7 / tubulin tyrosine ligase like 3ENSG0000021402113
ARPC4-TTLL3 / ARPC4-TTLL3 readthroughENSG0000025015110


Protein motifs (from Interpro)
Interpro ID Name
 IPR004344  Tubulin-tyrosine ligase/Tubulin polyglutamylase
 IPR027754  Tubulin polyglutamylase TTLL6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001578 microtubule bundle formation IEA
 biological_processGO:0003353 positive regulation of cilium movement IEA
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0018095 protein polyglutamylation IEA
 biological_processGO:0051013 microtubule severing IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium IEA
 cellular_componentGO:0036064 ciliary basal body IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015631 tubulin binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0070739 protein-glutamic acid ligase activity IEA
 molecular_functionGO:0070740 tubulin-glutamic acid ligase activity TAS


Pathways (from Reactome)
Pathway description
Carboxyterminal post-translational modifications of tubulin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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