ENSG00000100271


Homo sapiens

Features
Gene ID: ENSG00000100271
  
Biological name :TTLL1
  
Synonyms : O95922 / TTLL1 / tubulin tyrosine ligase like 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.2
Gene start: 43039644
Gene end: 43089428
  
Corresponding Affymetrix probe sets: 205652_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000403332
Ensembl peptide - ENSP00000266254
Ensembl peptide - ENSP00000333734
Ensembl peptide - ENSP00000401518
NCBI entrez gene - 25809     See in Manteia.
OMIM - 608955
RefSeq - XM_017028753
RefSeq - NM_012263
RefSeq - XM_011530110
RefSeq - XM_017028751
RefSeq - XM_017028752
RefSeq - XM_006724225
RefSeq - XM_011530108
RefSeq Peptide - NP_036395
swissprot - O95922
swissprot - A0A024R4U6
Ensembl - ENSG00000100271
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttll1ENSDARG00000090778Danio rerio
 TTLL1ENSGALG00000014163Gallus gallus
 Ttll1ENSMUSG00000022442Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TTLL9 / Q3SXZ7 / tubulin tyrosine ligase like 9ENSG0000013104439
TTLL6 / Q8N841 / tubulin tyrosine ligase like 6ENSG0000017070329
A6NNM8 / TTLL13P / tubulin tyrosine ligase like 13, pseudogeneENSG0000021347128
TTLL5 / Q6EMB2 / tubulin tyrosine ligase like 5ENSG0000011968528
TTLL2 / Q9BWV7 / tubulin tyrosine ligase like 2ENSG0000012044028
TTLL4 / Q14679 / tubulin tyrosine ligase like 4ENSG0000013591226
TTLL7 / Q6ZT98 / tubulin tyrosine ligase like 7ENSG0000013794125
Q8NHH1 / TTLL11 / tubulin tyrosine ligase like 11ENSG0000017576424
Q6ZVT0 / TTLL10 / tubulin tyrosine ligase like 10ENSG0000016257121
TTLL8 / A6PVC2 / tubulin tyrosine ligase like 8ENSG0000013889220
TTLL3 / Q9Y4R7 / tubulin tyrosine ligase like 3ENSG0000021402119
ARPC4-TTLL3 / ARPC4-TTLL3 readthroughENSG0000025015119


Protein motifs (from Interpro)
Interpro ID Name
 IPR004344  Tubulin-tyrosine ligase/Tubulin polyglutamylase
 IPR027750  Tubulin polyglutamylase TTLL1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003351 epithelial cilium movement IEA
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0007288 sperm axoneme assembly IEA
 biological_processGO:0018095 protein polyglutamylation TAS
 biological_processGO:0035082 axoneme assembly IEA
 biological_processGO:1905419 sperm flagellum movement involved in flagellated sperm motility IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0070740 tubulin-glutamic acid ligase activity TAS


Pathways (from Reactome)
Pathway description
Carboxyterminal post-translational modifications of tubulin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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