ENSG00000214021


Homo sapiens

Features
Gene ID: ENSG00000214021
  
Biological name :TTLL3
  
Synonyms : Q9Y4R7 / TTLL3 / tubulin tyrosine ligase like 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.3
Gene start: 9808086
Gene end: 9855138
  
Corresponding Affymetrix probe sets: 1555474_at (Human Genome U133 Plus 2.0 Array)   1555475_x_at (Human Genome U133 Plus 2.0 Array)   203670_at (Human Genome U133 Plus 2.0 Array)   210129_s_at (Human Genome U133 Plus 2.0 Array)   230872_s_at (Human Genome U133 Plus 2.0 Array)   230873_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000402197
Ensembl peptide - ENSP00000408128
Ensembl peptide - ENSP00000409246
Ensembl peptide - ENSP00000409632
Ensembl peptide - ENSP00000412915
Ensembl peptide - ENSP00000414965
Ensembl peptide - ENSP00000430051
Ensembl peptide - ENSP00000473314
Ensembl peptide - ENSP00000473376
Ensembl peptide - ENSP00000473440
Ensembl peptide - ENSP00000312148
Ensembl peptide - ENSP00000373338
Ensembl peptide - ENSP00000389904
Ensembl peptide - ENSP00000392549
Ensembl peptide - ENSP00000394481
Ensembl peptide - ENSP00000395912
Ensembl peptide - ENSP00000396606
Ensembl peptide - ENSP00000400462
Ensembl peptide - ENSP00000401686
Ensembl peptide - ENSP00000403874
Ensembl peptide - ENSP00000398097
Ensembl peptide - ENSP00000398996
Ensembl peptide - ENSP00000399191
Ensembl peptide - ENSP00000399782
Ensembl peptide - ENSP00000399930
NCBI entrez gene - 26140     See in Manteia.
RefSeq - NM_001025930
RefSeq Peptide - NP_001021100
swissprot - R4GN12
swissprot - C9IZU0
swissprot - C9JKU2
swissprot - C9JNK2
swissprot - C9JNK7
swissprot - C9JQ30
swissprot - C9JRM2
swissprot - C9JSD3
swissprot - C9JUK0
swissprot - C9JW59
swissprot - C9JWZ9
swissprot - C9JZ73
swissprot - E5RGZ6
swissprot - F8WBP6
swissprot - F8WD18
swissprot - H0Y5E3
swissprot - H3BLT7
swissprot - H7C0T5
swissprot - H7C197
swissprot - J3KQB2
swissprot - Q9Y4R7
swissprot - R4GMR7
swissprot - R4GMW2
Ensembl - ENSG00000214021
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttll3ENSDARG00000053728Danio rerio
 ENSGALG00000044133Gallus gallus
 Ttll3ENSMUSG00000030276Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARPC4-TTLL3 / ARPC4-TTLL3 readthroughENSG0000025015155
TTLL8 / A6PVC2 / tubulin tyrosine ligase like 8ENSG0000013889233
TTLL6 / Q8N841 / tubulin tyrosine ligase like 6ENSG0000017070313
TTLL5 / Q6EMB2 / tubulin tyrosine ligase like 5ENSG0000011968512
A6NNM8 / TTLL13P / tubulin tyrosine ligase like 13, pseudogeneENSG0000021347112
TTLL7 / Q6ZT98 / tubulin tyrosine ligase like 7ENSG0000013794112
TTLL4 / Q14679 / tubulin tyrosine ligase like 4ENSG0000013591211
Q8NHH1 / TTLL11 / tubulin tyrosine ligase like 11ENSG0000017576410
Q6ZVT0 / TTLL10 / tubulin tyrosine ligase like 10ENSG0000016257110
TTLL9 / Q3SXZ7 / tubulin tyrosine ligase like 9ENSG0000013104410
TTLL1 / O95922 / tubulin tyrosine ligase like 1ENSG000001002719
TTLL2 / Q9BWV7 / tubulin tyrosine ligase like 2ENSG000001204409


Protein motifs (from Interpro)
Interpro ID Name
 IPR004344  Tubulin-tyrosine ligase/Tubulin polyglutamylase
 IPR013815  ATP-grasp fold, subdomain 1
 IPR027753  Tubulin monoglycylase TTLL3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0018094 protein polyglycylation IEA
 biological_processGO:0035082 axoneme assembly ISS
 biological_processGO:0060271 cilium assembly ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium ISS
 cellular_componentGO:0005930 axoneme ISS
 cellular_componentGO:0015630 microtubule cytoskeleton ISS
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0070735 protein-glycine ligase activity IEA
 molecular_functionGO:0070736 protein-glycine ligase activity, initiating ISS


Pathways (from Reactome)
Pathway description
Carboxyterminal post-translational modifications of tubulin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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