ENSG00000138892


Homo sapiens

Features
Gene ID: ENSG00000138892
  
Biological name :TTLL8
  
Synonyms : A6PVC2 / TTLL8 / tubulin tyrosine ligase like 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.33
Gene start: 50015123
Gene end: 50056935
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000266182
Ensembl peptide - ENSP00000392252
RefSeq - XM_017029176
swissprot - A0A1C7CYW9
swissprot - A6PVC2
Ensembl - ENSG00000138892
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ttll8ENSMUSG00000022388Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TTLL3 / Q9Y4R7 / tubulin tyrosine ligase like 3ENSG0000021402135
ARPC4-TTLL3 / ARPC4-TTLL3 readthroughENSG0000025015128
TTLL6 / Q8N841 / tubulin tyrosine ligase like 6ENSG0000017070314
TTLL5 / Q6EMB2 / tubulin tyrosine ligase like 5ENSG0000011968514
A6NNM8 / TTLL13P / tubulin tyrosine ligase like 13, pseudogeneENSG0000021347113
TTLL7 / Q6ZT98 / tubulin tyrosine ligase like 7ENSG0000013794112
Q6ZVT0 / TTLL10 / tubulin tyrosine ligase like 10ENSG0000016257112
TTLL4 / Q14679 / tubulin tyrosine ligase like 4ENSG0000013591211
Q8NHH1 / TTLL11 / tubulin tyrosine ligase like 11ENSG0000017576411
TTLL9 / Q3SXZ7 / tubulin tyrosine ligase like 9ENSG0000013104411
TTLL2 / Q9BWV7 / tubulin tyrosine ligase like 2ENSG0000012044010
TTLL1 / O95922 / tubulin tyrosine ligase like 1ENSG0000010027110


Protein motifs (from Interpro)
Interpro ID Name
 IPR004344  Tubulin-tyrosine ligase/Tubulin polyglutamylase
 IPR013815  ATP-grasp fold, subdomain 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006464 cellular protein modification process IEA
 biological_processGO:0018094 protein polyglycylation TAS
 biological_processGO:0060271 cilium assembly IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005929 cilium ISS
 cellular_componentGO:0005930 axoneme ISS
 cellular_componentGO:0015630 microtubule cytoskeleton ISS
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0070735 protein-glycine ligase activity TAS
 molecular_functionGO:0070736 protein-glycine ligase activity, initiating ISS


Pathways (from Reactome)
Pathway description
Carboxyterminal post-translational modifications of tubulin


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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