ENSG00000136518


Homo sapiens

Features
Gene ID: ENSG00000136518
  
Biological name :ACTL6A
  
Synonyms : actin like 6A / ACTL6A / O96019
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q26.33
Gene start: 179562880
Gene end: 179588408
  
Corresponding Affymetrix probe sets: 202666_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376430
Ensembl peptide - ENSP00000397552
Ensembl peptide - ENSP00000420153
Ensembl peptide - ENSP00000420694
Ensembl peptide - ENSP00000394014
NCBI entrez gene - 86     See in Manteia.
OMIM - 604958
RefSeq - NM_004301
RefSeq - NM_178042
RefSeq - NM_177989
RefSeq Peptide - NP_004292
RefSeq Peptide - NP_829888
RefSeq Peptide - NP_817126
swissprot - O96019
swissprot - C9JQT2
swissprot - H7C5S0
Ensembl - ENSG00000136518
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 actl6aENSDARG00000070828Danio rerio
 ACTL6AENSGALG00000009061Gallus gallus
 Actl6aENSMUSG00000027671Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACTL6B / O94805 / actin like 6BENSG0000007708083


Protein motifs (from Interpro)
Interpro ID Name
 IPR004000  Actin family
 IPR004001  Actin, conserved site
 IPR029912  Actin-like protein 6A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003407 neural retina development IEP
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II NAS
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0021510 spinal cord development IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0043044 ATP-dependent chromatin remodeling HDA
 biological_processGO:0043967 histone H4 acetylation IDA
 biological_processGO:0043968 histone H2A acetylation IDA
 cellular_componentGO:0000790 nuclear chromatin HDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016514 SWI/SNF complex IDA
 cellular_componentGO:0031011 Ino80 complex IDA
 cellular_componentGO:0032991 protein-containing complex HDA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IDA
 cellular_componentGO:0071564 npBAF complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding HDA
 molecular_functionGO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding HDA
 molecular_functionGO:0003682 chromatin binding TAS
 molecular_functionGO:0003713 transcription coactivator activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031492 nucleosomal DNA binding HDA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
RMTs methylate histone arginines
UCH proteinases
DNA Damage Recognition in GG-NER
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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