ENSG00000138472


Homo sapiens

Features
Gene ID: ENSG00000138472
  
Biological name :GUCA1C
  
Synonyms : guanylate cyclase activator 1C / GUCA1C / O95843
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q13.13
Gene start: 108907792
Gene end: 108953895
  
Corresponding Affymetrix probe sets: 223928_s_at (Human Genome U133 Plus 2.0 Array)   233902_at (Human Genome U133 Plus 2.0 Array)   233953_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000261047
Ensembl peptide - ENSP00000417761
Ensembl peptide - ENSP00000377535
NCBI entrez gene - 9626     See in Manteia.
OMIM - 605128
RefSeq - XM_005247910
RefSeq - XM_011513334
RefSeq - NM_005459
RefSeq Peptide - NP_005450
swissprot - O95843
swissprot - C9JNI2
swissprot - C9J7M7
Ensembl - ENSG00000138472
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 guca1cENSDARG00000030758Danio rerio
 guca1dENSDARG00000044629Danio rerio
 GUCA1CENSGALG00000015364Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GUCA1A / P43080 / guanylate cyclase activator 1AENSG0000004854544
NCALD / P61601 / neurocalcin deltaENSG0000010449031
GUCA1B / Q9UMX6 / guanylate cyclase activator 1BENSG0000011259931
HPCAL1 / P37235 / hippocalcin like 1ENSG0000011575631
HPCA / P84074 / hippocalcinENSG0000012190529
NCS1 / P62166 / neuronal calcium sensor 1ENSG0000010713027
HPCAL4 / Q9UM19 / hippocalcin like 4ENSG0000011698326
KCNIP2 / Q9NS61 / potassium voltage-gated channel interacting protein 2ENSG0000012004926
VSNL1 / P62760 / visinin like 1ENSG0000016303226
RCVRN / P35243 / recoverinENSG0000010904725
KCNIP3 / Q9Y2W7 / potassium voltage-gated channel interacting protein 3ENSG0000011504123
KCNIP4 / Q6PIL6 / potassium voltage-gated channel interacting protein 4ENSG0000018577423
KCNIP1 / Q9NZI2 / potassium voltage-gated channel interacting protein 1ENSG0000018213223


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site
 IPR032992  Guanylyl cyclase-activating protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0022400 regulation of rhodopsin mediated signaling pathway TAS
 biological_processGO:0031282 regulation of guanylate cyclase activity IEA
 biological_processGO:0031284 positive regulation of guanylate cyclase activity IEA
 cellular_componentGO:0097381 photoreceptor disc membrane TAS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008048 calcium sensitive guanylate cyclase activator activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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