ENSG00000140022


Homo sapiens

Features
Gene ID: ENSG00000140022
  
Biological name :STON2
  
Synonyms : Q8WXE9 / STON2 / stonin 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q31.1
Gene start: 81260656
Gene end: 81436465
  
Corresponding Affymetrix probe sets: 1552543_a_at (Human Genome U133 Plus 2.0 Array)   227461_at (Human Genome U133 Plus 2.0 Array)   235852_at (Human Genome U133 Plus 2.0 Array)   242583_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477736
Ensembl peptide - ENSP00000450990
Ensembl peptide - ENSP00000451383
Ensembl peptide - ENSP00000267540
Ensembl peptide - ENSP00000450577
Ensembl peptide - ENSP00000450857
NCBI entrez gene - 85439     See in Manteia.
OMIM - 608467
RefSeq - XM_011537242
RefSeq - NM_001256430
RefSeq - NM_033104
RefSeq - XM_006720279
RefSeq - XM_011537240
RefSeq - XM_011537241
RefSeq Peptide - NP_001243359
RefSeq Peptide - NP_149095
swissprot - H0YJ05
swissprot - Q8WXE9
swissprot - G3V322
Ensembl - ENSG00000140022
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ston2ENSDARG00000057452Danio rerio
 STON2ENSGALG00000010579Gallus gallus
 Ston2ENSMUSG00000020961Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
STON1-GTF2A1L / STON1-GTF2A1L readthroughENSG0000006878128
STON1 / Q9Y6Q2 / stonin 1ENSG0000024324427
Q9UNN4 / GTF2A1L / general transcription factor IIA subunit 1 likeENSG000002424419


Protein motifs (from Interpro)
Interpro ID Name
 IPR012320  Stonin homology
 IPR017110  Stonin
 IPR022699  Stonin-2, N-terminal
 IPR028565  Mu homology domain
 IPR031228  Stonin-2
 IPR036168  AP-2 complex subunit mu, C-terminal superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IEA
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0030100 regulation of endocytosis ISS
 biological_processGO:0036465 synaptic vesicle recycling IEA
 biological_processGO:0048488 synaptic vesicle endocytosis IGI
 biological_processGO:0061024 membrane organization TAS
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000067715 SYT1 / P21579 / synaptotagmin 1  / complex / reaction
 ENSG00000170743 SYT9 / Q86SS6 / synaptotagmin 9  / reaction / complex
 ENSG00000136827 TOR1A / O14656 / torsin family 1 member A  / complex / reaction
 ENSG00000143858 SYT2 / Q8N9I0 / synaptotagmin 2  / reaction / complex






 

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