ENSG00000170743


Homo sapiens

Features
Gene ID: ENSG00000170743
  
Biological name :SYT9
  
Synonyms : Q86SS6 / synaptotagmin 9 / SYT9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: p15.4
Gene start: 7238778
Gene end: 7469042
  
Corresponding Affymetrix probe sets: 1555052_a_at (Human Genome U133 Plus 2.0 Array)   1555053_at (Human Genome U133 Plus 2.0 Array)   1563658_a_at (Human Genome U133 Plus 2.0 Array)   232445_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000324419
Ensembl peptide - ENSP00000434558
Ensembl peptide - ENSP00000432141
NCBI entrez gene - 143425     See in Manteia.
OMIM - 613528
RefSeq - XM_011519900
RefSeq - XM_011519904
RefSeq - NM_175733
RefSeq - XM_011519901
RefSeq Peptide - NP_783860
swissprot - Q86SS6
swissprot - E9PDN4
swissprot - B3KNT7
Ensembl - ENSG00000170743
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syt9aENSDARG00000003994Danio rerio
 syt9bENSDARG00000029239Danio rerio
 SYT9ENSGALG00000005265Gallus gallus
 Syt9ENSMUSG00000062542Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYT10 / Q6XYQ8 / synaptotagmin 10ENSG0000011097560
SYT3 / Q9BQG1 / synaptotagmin 3ENSG0000021302354
SYT6 / Q5T7P8 / synaptotagmin 6ENSG0000013420752
SYT1 / P21579 / synaptotagmin 1ENSG0000006771531
SYT5 / O00445 / synaptotagmin 5ENSG0000012999030
SYT2 / Q8N9I0 / synaptotagmin 2ENSG0000014385830
SYT7 / O43581 / synaptotagmin 7ENSG0000001134728
SYT4 / Q9H2B2 / synaptotagmin 4ENSG0000013287226
SYT11 / Q9BT88 / synaptotagmin 11ENSG0000013271825
SYT8 / Q8NBV8 / synaptotagmin 8ENSG0000014904323


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR028691  Synaptotagmin-9
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0045956 positive regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 biological_processGO:0050796 regulation of insulin secretion IEA
 biological_processGO:0061024 membrane organization TAS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0030665 clathrin-coated vesicle membrane TAS
 cellular_componentGO:0030667 secretory granule membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031045 dense core granule IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0000149 SNARE binding IEA
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000140022 STON2 / Q8WXE9 / stonin 2  / complex / reaction
 ENSG00000170743 SYT9 / Q86SS6 / synaptotagmin 9  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr