ENSG00000134207


Homo sapiens

Features
Gene ID: ENSG00000134207
  
Biological name :SYT6
  
Synonyms : Q5T7P8 / synaptotagmin 6 / SYT6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p13.2
Gene start: 114089291
Gene end: 114153919
  
Corresponding Affymetrix probe sets: 244227_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477325
Ensembl peptide - ENSP00000493062
Ensembl peptide - ENSP00000477344
Ensembl peptide - ENSP00000358560
Ensembl peptide - ENSP00000476324
Ensembl peptide - ENSP00000476396
Ensembl peptide - ENSP00000476507
Ensembl peptide - ENSP00000476562
Ensembl peptide - ENSP00000476616
Ensembl peptide - ENSP00000477219
NCBI entrez gene - 148281     See in Manteia.
OMIM - 607718
RefSeq - NM_205848
RefSeq - XM_017000371
RefSeq - NM_001270805
RefSeq Peptide - NP_995320
RefSeq Peptide - NP_001257734
swissprot - A0A286YEX2
swissprot - Q5T7P8
swissprot - V9GY33
swissprot - V9GYB1
swissprot - V9GYC4
swissprot - V9GYY7
swissprot - I6L9C3
Ensembl - ENSG00000134207
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syt6aENSDARG00000076730Danio rerio
 syt6bENSDARG00000031463Danio rerio
 SYT6ENSGALG00000001968Gallus gallus
 Syt6ENSMUSG00000027849Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYT10 / Q6XYQ8 / synaptotagmin 10ENSG0000011097569
SYT9 / Q86SS6 / synaptotagmin 9ENSG0000017074360
SYT3 / Q9BQG1 / synaptotagmin 3ENSG0000021302351
SYT1 / P21579 / synaptotagmin 1ENSG0000006771535
SYT5 / O00445 / synaptotagmin 5ENSG0000012999035
SYT2 / Q8N9I0 / synaptotagmin 2ENSG0000014385834
SYT7 / O43581 / synaptotagmin 7ENSG0000001134732
SYT11 / Q9BT88 / synaptotagmin 11ENSG0000013271830
SYT4 / Q9H2B2 / synaptotagmin 4ENSG0000013287230
SYT8 / Q8NBV8 / synaptotagmin 8ENSG0000014904324


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR028701  Synaptotagmin-6
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0007340 acrosome reaction IEA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 biological_processGO:0060478 acrosomal vesicle exocytosis IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0019898 extrinsic component of membrane ISS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0097038 perinuclear endoplasmic reticulum ISS
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IEA
 molecular_functionGO:0019905 syntaxin binding IDA
 molecular_functionGO:0030276 clathrin binding IDA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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