ENSMUSG00000027849


Mus musculus

Features
Gene ID: ENSMUSG00000027849
  
Biological name :Syt6
  
Synonyms : Q9R0N8 / synaptotagmin VI / Syt6
  
Possible biological names infered from orthology : Q5T7P8 / synaptotagmin 6
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F2.2
Gene start: 103575231
Gene end: 103645569
  
Corresponding Affymetrix probe sets: 10494945 (MoGene1.0st)   1420188_at (Mouse Genome 430 2.0 Array)   1426106_a_at (Mouse Genome 430 2.0 Array)   1449766_at (Mouse Genome 430 2.0 Array)   1449767_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000119688
Ensembl peptide - ENSMUSP00000118124
Ensembl peptide - ENSMUSP00000138874
Ensembl peptide - ENSMUSP00000088196
Ensembl peptide - ENSMUSP00000112486
Ensembl peptide - ENSMUSP00000112997
Ensembl peptide - ENSMUSP00000113287
Ensembl peptide - ENSMUSP00000113373
Ensembl peptide - ENSMUSP00000116324
NCBI entrez gene - 54524     See in Manteia.
MGI - MGI:1859544
RefSeq - XM_006501708
RefSeq - NM_001276676
RefSeq - NM_001276677
RefSeq - NM_001276679
RefSeq - NM_001276680
RefSeq - NM_001276681
RefSeq - NM_018800
RefSeq - XM_006501704
RefSeq - XM_006501705
RefSeq - XM_006501706
RefSeq - XM_006501707
RefSeq Peptide - NP_001263609
RefSeq Peptide - NP_001263610
RefSeq Peptide - NP_061270
RefSeq Peptide - NP_001263605
RefSeq Peptide - NP_001263606
RefSeq Peptide - NP_001263608
swissprot - Q8C8S6
swissprot - Q9R0N8
swissprot - V9GWX4
swissprot - D6RHQ5
swissprot - D6RIM4
swissprot - Q3UY13
swissprot - Q6P1H9
Ensembl - ENSMUSG00000027849
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syt6aENSDARG00000076730Danio rerio
 syt6bENSDARG00000031463Danio rerio
 SYT6ENSGALG00000001968Gallus gallus
 SYT6ENSG00000134207Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Syt10 / Q9R0N4 / synaptotagmin X / Q6XYQ8* / synaptotagmin 10*ENSMUSG0000006326063
Syt9 / Q9R0N9 / Synaptotagmin-9 / Q86SS6*ENSMUSG0000006254255
Syt3 / synaptotagmin III / Q9BQG1* / synaptotagmin 3*ENSMUSG0000003073149
Syt1 / P46096 / synaptotagmin I / P21579* / synaptotagmin 1*ENSMUSG0000003586431
Syt5 / Q9R0N5 / Synaptotagmin-5 / O00445*ENSMUSG0000000496131
Syt7 / Q9R0N7 / Synaptotagmin-7 / O43581*ENSMUSG0000002474330
Syt2 / synaptotagmin II / Q8N9I0* / synaptotagmin 2*ENSMUSG0000002645230
Syt11 / Q9R0N3 / Synaptotagmin-11 / Q9BT88*ENSMUSG0000006892327
Syt4 / P40749 / Synaptotagmin-4 / Q9H2B2*ENSMUSG0000002426125
Syt8 / Q9R0N6 / synaptotagmin VIII / Q8NBV8* / synaptotagmin 8*ENSMUSG0000003109822


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR028701  Synaptotagmin-6
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0007340 acrosome reaction IDA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 biological_processGO:0060478 acrosomal vesicle exocytosis IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0097038 perinuclear endoplasmic reticulum IDA
 molecular_functionGO:0001786 phosphatidylserine binding IDA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IDA
 molecular_functionGO:0019905 syntaxin binding IEA
 molecular_functionGO:0030276 clathrin binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Tyrp1rgsc220/Tyrp1rgsc220
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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