ENSMUSG00000063260


Mus musculus

Features
Gene ID: ENSMUSG00000063260
  
Biological name :Syt10
  
Synonyms : Q9R0N4 / synaptotagmin X / Syt10
  
Possible biological names infered from orthology : Q6XYQ8 / synaptotagmin 10
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E3
Gene start: 89782393
Gene end: 89841860
  
Corresponding Affymetrix probe sets: 10431625 (MoGene1.0st)   1450347_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029441
NCBI entrez gene - 54526     See in Manteia.
MGI - MGI:1859546
RefSeq - XM_017316706
RefSeq - NM_018803
RefSeq - XM_006521175
RefSeq - XM_011245696
RefSeq Peptide - NP_061273
swissprot - Q059J3
swissprot - Q9R0N4
Ensembl - ENSMUSG00000063260
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syt10ENSDARG00000045750Danio rerio
 SYT10ENSGALG00000012911Gallus gallus
 SYT10ENSG00000110975Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Syt6 / Q9R0N8 / synaptotagmin VI / Q5T7P8* / synaptotagmin 6*ENSMUSG0000002784962
Syt9 / Q9R0N9 / Synaptotagmin-9 / Q86SS6*ENSMUSG0000006254256
Syt3 / synaptotagmin III / Q9BQG1* / synaptotagmin 3*ENSMUSG0000003073149
Syt1 / P46096 / synaptotagmin I / P21579* / synaptotagmin 1*ENSMUSG0000003586430
Syt2 / synaptotagmin II / Q8N9I0* / synaptotagmin 2*ENSMUSG0000002645229
Syt7 / Q9R0N7 / Synaptotagmin-7 / O43581*ENSMUSG0000002474328
Syt5 / Q9R0N5 / Synaptotagmin-5 / O00445*ENSMUSG0000000496127
Syt11 / Q9R0N3 / Synaptotagmin-11 / Q9BT88*ENSMUSG0000006892325
Syt4 / P40749 / Synaptotagmin-4 / Q9H2B2*ENSMUSG0000002426124
Syt8 / Q9R0N6 / synaptotagmin VIII / Q8NBV8* / synaptotagmin 8*ENSMUSG0000003109820


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR028677  Synaptotagmin-10
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0007268 chemical synaptic transmission IMP
 biological_processGO:0007608 sensory perception of smell IMP
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IMP
 biological_processGO:0045956 positive regulation of calcium ion-dependent exocytosis IMP
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0070382 exocytic vesicle IDA
 molecular_functionGO:0000149 SNARE binding IDA
 molecular_functionGO:0001786 phosphatidylserine binding IDA
 molecular_functionGO:0005509 calcium ion binding IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IDA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tyrp1rgsc220/Tyrp1rgsc220
Genetic Background: involves: C57BL/6JJcl * DBA/2JJcl

 MP:0020467 abnormal circadian behavior "any anomaly in the specific behavior of an organism that recurs with a regularity of approximately 24 hours" [GO:0048512]
Show

Allelic Composition: Arntltm1Bra/Arntltm1Weit,Syt10tm1.1(icre)Geno/Syt10+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Arntltm1Bra/Arntltm1Bra,Syt10tm1.1(icre)Geno/Syt10tm1.1(icre)Geno
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Arntltm1Bra/Arntltm1Weit,Syt10tm1.1(icre)Geno/Syt10tm1.1(icre)Geno
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6

 MP:0020470 shortened circadian behavior period "decrease in the cycle length of a behavior expressed when exposed to constant conditions without temporal cues" [MGI:smb]
Show

Allelic Composition: Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob,Tg(Col10a1-cre)1427Vdm/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6

Allelic Composition: Arntltm1Weit/Arntltm1Weit,Syt10tm1.1(icre)Geno/Syt10+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6

Allelic Composition: Arntltm1Bra/Arntltm1Weit,Syt10tm1.1(icre)Geno/Syt10+
Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6

 MP:0020474 advanced circadian behavior phase "increase in the phase relationship between a temporal synchronizing event (such as light cycle) and a behavioral phase reference point of an animal (such as activity onset)" [MGI:smb]
Show

Allelic Composition: Tnfsf11tm1.1Caob/Tnfsf11tm1.1Caob,Tg(Col10a1-cre)1427Vdm/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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