ENSMUSG00000062542


Mus musculus

Features
Gene ID: ENSMUSG00000062542
  
Biological name :Syt9
  
Synonyms : Q9R0N9 / Synaptotagmin-9 / Syt9
  
Possible biological names infered from orthology : Q86SS6
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: E3
Gene start: 107370728
Gene end: 107548656
  
Corresponding Affymetrix probe sets: 10556067 (MoGene1.0st)   1423258_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000073164
Ensembl peptide - ENSMUSP00000122049
Ensembl peptide - ENSMUSP00000117969
NCBI entrez gene - 60510     See in Manteia.
MGI - MGI:1926373
RefSeq - NM_021889
RefSeq - XM_006508099
RefSeq Peptide - NP_068689
swissprot - D6RGS5
swissprot - Q9R0N9
swissprot - D3YVX0
Ensembl - ENSMUSG00000062542
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syt9aENSDARG00000003994Danio rerio
 syt9bENSDARG00000029239Danio rerio
 SYT9ENSGALG00000005265Gallus gallus
 SYT9ENSG00000170743Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Syt10 / Q9R0N4 / synaptotagmin X / Q6XYQ8* / synaptotagmin 10*ENSMUSG0000006326060
Syt6 / Q9R0N8 / synaptotagmin VI / Q5T7P8* / synaptotagmin 6*ENSMUSG0000002784957
Syt3 / synaptotagmin III / Q9BQG1* / synaptotagmin 3*ENSMUSG0000003073153
Syt1 / P46096 / synaptotagmin I / P21579* / synaptotagmin 1*ENSMUSG0000003586431
Syt7 / Q9R0N7 / Synaptotagmin-7 / O43581*ENSMUSG0000002474331
Syt2 / synaptotagmin II / Q8N9I0* / synaptotagmin 2*ENSMUSG0000002645230
Syt5 / Q9R0N5 / Synaptotagmin-5 / O00445*ENSMUSG0000000496130
Syt4 / P40749 / Synaptotagmin-4 / Q9H2B2*ENSMUSG0000002426126
Syt11 / Q9R0N3 / Synaptotagmin-11 / Q9BT88*ENSMUSG0000006892325
Syt8 / Q9R0N6 / synaptotagmin VIII / Q8NBV8* / synaptotagmin 8*ENSMUSG0000003109823


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR028691  Synaptotagmin-9
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IMP
 biological_processGO:0045956 positive regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 biological_processGO:0050796 regulation of insulin secretion IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030141 secretory granule IEA
 cellular_componentGO:0030667 secretory granule membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031045 dense core granule IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0000149 SNARE binding IDA
 molecular_functionGO:0001786 phosphatidylserine binding IDA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IDA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020961 Ston2 / Q8BZ60 / Stonin-2 / Q8WXE9*  / reaction / complex
 ENSMUSG00000062542 Syt9 / Q9R0N9 / Synaptotagmin-9 / Q86SS6*  / complex






 

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contact: otassy@igbmc.fr