ENSMUSG00000031098


Mus musculus

Features
Gene ID: ENSMUSG00000031098
  
Biological name :Syt8
  
Synonyms : Q9R0N6 / synaptotagmin VIII / Syt8
  
Possible biological names infered from orthology : Q8NBV8 / synaptotagmin 8
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F5
Gene start: 142434850
Gene end: 142440396
  
Corresponding Affymetrix probe sets: 10559185 (MoGene1.0st)   1450800_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113545
Ensembl peptide - ENSMUSP00000112689
Ensembl peptide - ENSMUSP00000147572
Ensembl peptide - ENSMUSP00000095552
Ensembl peptide - ENSMUSP00000101596
Ensembl peptide - ENSMUSP00000101597
NCBI entrez gene - 55925     See in Manteia.
MGI - MGI:1859867
RefSeq - XM_011242020
RefSeq - XM_006508638
RefSeq - XM_006508639
RefSeq - XM_006508640
RefSeq - XM_011242014
RefSeq - XM_011242015
RefSeq - XM_011242016
RefSeq - XM_011242017
RefSeq - XM_011242018
RefSeq - NM_001285857
RefSeq - NM_001285858
RefSeq - NM_001285861
RefSeq - NM_018802
RefSeq - XM_006508632
RefSeq - XM_006508633
RefSeq - XM_006508635
RefSeq - XM_006508637
RefSeq Peptide - NP_001272790
RefSeq Peptide - NP_061272
RefSeq Peptide - NP_001272786
RefSeq Peptide - NP_001272787
swissprot - Q9R0N6
swissprot - E9Q6P7
swissprot - F2Z3W8
swissprot - A0A1B0GRL5
Ensembl - ENSMUSG00000031098
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SYT8ENSGALG00000006602Gallus gallus
 SYT8ENSG00000149043Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Syt1 / P46096 / synaptotagmin I / P21579* / synaptotagmin 1*ENSMUSG0000003586438
Syt2 / synaptotagmin II / Q8N9I0* / synaptotagmin 2*ENSMUSG0000002645238
Syt5 / Q9R0N5 / Synaptotagmin-5 / O00445*ENSMUSG0000000496137
Syt6 / Q9R0N8 / synaptotagmin VI / Q5T7P8* / synaptotagmin 6*ENSMUSG0000002784928
Syt3 / synaptotagmin III / Q9BQG1* / synaptotagmin 3*ENSMUSG0000003073128
Syt9 / Q9R0N9 / Synaptotagmin-9 / Q86SS6*ENSMUSG0000006254228
Syt10 / Q9R0N4 / synaptotagmin X / Q6XYQ8* / synaptotagmin 10*ENSMUSG0000006326027
Syt7 / Q9R0N7 / Synaptotagmin-7 / O43581*ENSMUSG0000002474327
Syt4 / P40749 / Synaptotagmin-4 / Q9H2B2*ENSMUSG0000002426126
Syt11 / Q9R0N3 / Synaptotagmin-11 / Q9BT88*ENSMUSG0000006892326


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR030540  Synaptotagmin-8
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0007340 acrosome reaction IDA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0048488 synaptic vesicle endocytosis IBA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IBA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031982 vesicle IDA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0048306 calcium-dependent protein binding IPI


Pathways (from Reactome)
Pathway description
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000031098 Syt8 / Q9R0N6 / synaptotagmin VIII / Q8NBV8* / synaptotagmin 8*  / complex






 

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contact: otassy@igbmc.fr