ENSG00000110975


Homo sapiens

Features
Gene ID: ENSG00000110975
  
Biological name :SYT10
  
Synonyms : Q6XYQ8 / synaptotagmin 10 / SYT10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: p11.1
Gene start: 33374238
Gene end: 33439819
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000228567
Ensembl peptide - ENSP00000444577
NCBI entrez gene - 341359     See in Manteia.
RefSeq - XM_011520644
RefSeq - NM_198992
RefSeq Peptide - NP_945343
swissprot - Q6XYQ8
swissprot - F5GZB8
Ensembl - ENSG00000110975
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syt10ENSDARG00000045750Danio rerio
 SYT10ENSGALG00000012911Gallus gallus
 Syt10ENSMUSG00000063260Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYT6 / Q5T7P8 / synaptotagmin 6ENSG0000013420756
SYT9 / Q86SS6 / synaptotagmin 9ENSG0000017074356
SYT3 / Q9BQG1 / synaptotagmin 3ENSG0000021302350
SYT1 / P21579 / synaptotagmin 1ENSG0000006771531
SYT2 / Q8N9I0 / synaptotagmin 2ENSG0000014385829
SYT5 / O00445 / synaptotagmin 5ENSG0000012999028
SYT7 / O43581 / synaptotagmin 7ENSG0000001134726
SYT4 / Q9H2B2 / synaptotagmin 4ENSG0000013287226
SYT11 / Q9BT88 / synaptotagmin 11ENSG0000013271825
SYT8 / Q8NBV8 / synaptotagmin 8ENSG0000014904322


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR028677  Synaptotagmin-10
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007608 sensory perception of smell IEA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0045956 positive regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070382 exocytic vesicle IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0000149 SNARE binding IEA
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IBA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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