ENSG00000011347


Homo sapiens

Features
Gene ID: ENSG00000011347
  
Biological name :SYT7
  
Synonyms : O43581 / synaptotagmin 7 / SYT7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.2
Gene start: 61515313
Gene end: 61581148
  
Corresponding Affymetrix probe sets: 1559392_s_at (Human Genome U133 Plus 2.0 Array)   1559956_at (Human Genome U133 Plus 2.0 Array)   226167_at (Human Genome U133 Plus 2.0 Array)   231025_at (Human Genome U133 Plus 2.0 Array)   232025_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444568
Ensembl peptide - ENSP00000444019
Ensembl peptide - ENSP00000444201
Ensembl peptide - ENSP00000263846
Ensembl peptide - ENSP00000437720
Ensembl peptide - ENSP00000438171
Ensembl peptide - ENSP00000439694
Ensembl peptide - ENSP00000441184
Ensembl peptide - ENSP00000443576
NCBI entrez gene - 9066     See in Manteia.
OMIM - 604146
RefSeq - XM_011545343
RefSeq - XM_011545336
RefSeq - XM_011545337
RefSeq - XM_011545338
RefSeq - XM_011545339
RefSeq - XM_011545340
RefSeq - XM_011545341
RefSeq - NM_001252065
RefSeq - NM_001300773
RefSeq - NM_004200
RefSeq - XM_005274383
RefSeq - XM_005274384
RefSeq - XM_005274385
RefSeq - XM_011545335
RefSeq Peptide - NP_004191
RefSeq Peptide - NP_001238994
RefSeq Peptide - NP_001287702
swissprot - F5H8G7
swissprot - O43581
swissprot - F5GX00
Ensembl - ENSG00000011347
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 syt7aENSDARG00000063568Danio rerio
 syt7bENSDARG00000078060Danio rerio
 SYT7ENSGALG00000043139Gallus gallus
 Syt7ENSMUSG00000024743Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SYT2 / Q8N9I0 / synaptotagmin 2ENSG0000014385831
SYT1 / P21579 / synaptotagmin 1ENSG0000006771530
SYT3 / Q9BQG1 / synaptotagmin 3ENSG0000021302330
SYT11 / Q9BT88 / synaptotagmin 11ENSG0000013271829
SYT9 / Q86SS6 / synaptotagmin 9ENSG0000017074329
SYT5 / O00445 / synaptotagmin 5ENSG0000012999029
SYT10 / Q6XYQ8 / synaptotagmin 10ENSG0000011097528
SYT6 / Q5T7P8 / synaptotagmin 6ENSG0000013420728
SYT4 / Q9H2B2 / synaptotagmin 4ENSG0000013287228
SYT8 / Q8NBV8 / synaptotagmin 8ENSG0000014904322


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR001565  Synaptotagmin
 IPR015427  Synaptotagmin 7
 IPR015428  Synaptotagmin 1/2
 IPR035892  C2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001778 plasma membrane repair ISS
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0006909 phagocytosis ISS
 biological_processGO:0007269 neurotransmitter secretion IEA
 biological_processGO:0014059 regulation of dopamine secretion IEA
 biological_processGO:0017156 calcium ion regulated exocytosis IEA
 biological_processGO:0017158 regulation of calcium ion-dependent exocytosis IBA
 biological_processGO:0036465 synaptic vesicle recycling ISS
 biological_processGO:0045956 positive regulation of calcium ion-dependent exocytosis IEA
 biological_processGO:0046850 regulation of bone remodeling ISS
 biological_processGO:0048791 calcium ion-regulated exocytosis of neurotransmitter ISS
 biological_processGO:0050764 regulation of phagocytosis ISS
 biological_processGO:0050796 regulation of insulin secretion ISS
 biological_processGO:0070092 regulation of glucagon secretion ISS
 biological_processGO:0090119 vesicle-mediated cholesterol transport ISS
 biological_processGO:0090385 phagosome-lysosome fusion ISS
 biological_processGO:1990926 short-term synaptic potentiation ISS
 biological_processGO:1990927 calcium ion regulated lysosome exocytosis ISS
 cellular_componentGO:0005764 lysosome ISS
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005777 peroxisome ISS
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030658 transport vesicle membrane IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IEA
 cellular_componentGO:0031045 dense core granule IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032009 early phagosome ISS
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043195 terminal bouton IEA
 cellular_componentGO:0043679 axon terminus IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000149 SNARE binding IEA
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding ISS
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0019905 syntaxin binding IBA
 molecular_functionGO:0030276 clathrin binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neurexins and neuroligins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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