ENSG00000144848


Homo sapiens

Features
Gene ID: ENSG00000144848
  
Biological name :ATG3
  
Synonyms : ATG3 / autophagy related 3 / Q9NT62
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q13.2
Gene start: 112532509
Gene end: 112562046
  
Corresponding Affymetrix probe sets: 220237_at (Human Genome U133 Plus 2.0 Array)   221492_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420378
Ensembl peptide - ENSP00000283290
Ensembl peptide - ENSP00000385943
Ensembl peptide - ENSP00000420259
NCBI entrez gene - 64422     See in Manteia.
OMIM - 609606
RefSeq - XM_011513074
RefSeq - NM_001278712
RefSeq - NM_022488
RefSeq Peptide - NP_001265641
RefSeq Peptide - NP_071933
swissprot - C9JNW8
swissprot - F8WDI0
swissprot - Q9NT62
Ensembl - ENSG00000144848
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atg3ENSDARG00000009350Danio rerio
 ATG3ENSGALG00000015204Gallus gallus
 Atg3ENSMUSG00000022663Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007134  Autophagy-related protein 3, N-terminal
 IPR007135  Autophagy-related protein 3
 IPR019461  Autophagy-related protein 3, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006464 cellular protein modification process IDA
 biological_processGO:0006612 protein targeting to membrane ISS
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0043653 mitochondrial fragmentation involved in apoptotic process ISS
 biological_processGO:0044804 autophagy of nucleus IBA
 biological_processGO:0050765 negative regulation of phagocytosis IEA
 biological_processGO:1902017 regulation of cilium assembly ISS
 cellular_componentGO:0000153 cytoplasmic ubiquitin ligase complex IPI
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019776 Atg8 ligase activity ISS
 molecular_functionGO:0019777 Atg12 transferase activity ISS
 molecular_functionGO:0019787 ubiquitin-like protein transferase activity IDA
 molecular_functionGO:0019899 enzyme binding IPI


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000197548 ATG7 / O95352 / autophagy related 7  / complex / reaction
 ENSG00000085978 Q676U5 / ATG16L1 / autophagy related 16 like 1  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr