ENSG00000145536


Homo sapiens

Features
Gene ID: ENSG00000145536
  
Biological name :ADAMTS16
  
Synonyms : ADAM metallopeptidase with thrombospondin type 1 motif 16 / ADAMTS16 / Q8TE57
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: p15.32
Gene start: 5140330
Gene end: 5320304
  
Corresponding Affymetrix probe sets: 238125_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000274181
Ensembl peptide - ENSP00000421631
NCBI entrez gene - 170690     See in Manteia.
OMIM - 607510
RefSeq - NM_139056
RefSeq Peptide - NP_620687
swissprot - Q2XQZ0
swissprot - Q8TE57
Ensembl - ENSG00000145536
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adamts16ENSDARG00000074646Danio rerio
 Q69Z28ENSMUSG00000049538Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8TE60 / ADAMTS18 / ADAM metallopeptidase with thrombospondin type 1 motif 18ENSG0000014087356
Q9UKP4 / ADAMTS7 / ADAM metallopeptidase with thrombospondin type 1 motif 7ENSG0000013637835
P58397 / ADAMTS12 / ADAM metallopeptidase with thrombospondin type 1 motif 12ENSG0000015138834
Q9UKP5 / ADAMTS6 / ADAM metallopeptidase with thrombospondin type 1 motif 6ENSG0000004919233
Q9H324 / ADAMTS10 / ADAM metallopeptidase with thrombospondin type 1 motif 10ENSG0000014230332
Q8TE59 / ADAMTS19 / ADAM metallopeptidase with thrombospondin type 1 motif 19ENSG0000014580829
Q8TE56 / ADAMTS17 / ADAM metallopeptidase with thrombospondin type 1 motif 17ENSG0000014047028
O95450 / ADAMTS2 / ADAM metallopeptidase with thrombospondin type 1 motif 2ENSG0000008711628
Q8WXS8 / ADAMTS14 / ADAM metallopeptidase with thrombospondin type 1 motif 14ENSG0000013831627
O15072 / ADAMTS3 / ADAM metallopeptidase with thrombospondin type 1 motif 3ENSG0000015614027


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR002870  Peptidase M12B, propeptide
 IPR010294  ADAM-TS Spacer 1
 IPR010909  PLAC
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IEA
 biological_processGO:0003073 regulation of systemic arterial blood pressure IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0048232 male gamete generation IEA
 biological_processGO:1902017 regulation of cilium assembly IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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