ENSG00000138316


Homo sapiens

Features
Gene ID: ENSG00000138316
  
Biological name :ADAMTS14
  
Synonyms : ADAM metallopeptidase with thrombospondin type 1 motif 14 / ADAMTS14 / Q8WXS8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q22.1
Gene start: 70672803
Gene end: 70762441
  
Corresponding Affymetrix probe sets: 230167_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362303
Ensembl peptide - ENSP00000362304
NCBI entrez gene - 140766     See in Manteia.
OMIM - 607506
RefSeq - XM_011539309
RefSeq - NM_080722
RefSeq - NM_139155
RefSeq - XM_011539306
RefSeq - XM_011539307
RefSeq - XM_011539308
RefSeq - XM_011539300
RefSeq - XM_011539301
RefSeq - XM_011539302
RefSeq - XM_011539303
RefSeq - XM_011539305
RefSeq Peptide - NP_631894
RefSeq Peptide - NP_542453
swissprot - Q8WXS8
Ensembl - ENSG00000138316
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adamts14ENSDARG00000078494Danio rerio
 ADAMTS14ENSGALG00000039219Gallus gallus
 Adamts14ENSMUSG00000059901Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15072 / ADAMTS3 / ADAM metallopeptidase with thrombospondin type 1 motif 3ENSG0000015614054
O95450 / ADAMTS2 / ADAM metallopeptidase with thrombospondin type 1 motif 2ENSG0000008711652
Q8TE60 / ADAMTS18 / ADAM metallopeptidase with thrombospondin type 1 motif 18ENSG0000014087328
Q8TE57 / ADAMTS16 / ADAM metallopeptidase with thrombospondin type 1 motif 16ENSG0000014553627
Q9UKP4 / ADAMTS7 / ADAM metallopeptidase with thrombospondin type 1 motif 7ENSG0000013637827
Q9UKP5 / ADAMTS6 / ADAM metallopeptidase with thrombospondin type 1 motif 6ENSG0000004919227
Q9H324 / ADAMTS10 / ADAM metallopeptidase with thrombospondin type 1 motif 10ENSG0000014230327
Q8TE56 / ADAMTS17 / ADAM metallopeptidase with thrombospondin type 1 motif 17ENSG0000014047026
P58397 / ADAMTS12 / ADAM metallopeptidase with thrombospondin type 1 motif 12ENSG0000015138825
Q8TE59 / ADAMTS19 / ADAM metallopeptidase with thrombospondin type 1 motif 19ENSG0000014580825


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR010294  ADAM-TS Spacer 1
 IPR010909  PLAC
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0030199 collagen fibril organization IEA
 biological_processGO:0030574 collagen catabolic process IEA
 cellular_componentGO:0005576 extracellular region TAS
 molecular_functionGO:0004222 metalloendopeptidase activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Collagen biosynthesis and modifying enzymes
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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