ENSG00000145949


Homo sapiens

Features
Gene ID: ENSG00000145949
  
Biological name :MYLK4
  
Synonyms : MYLK4 / myosin light chain kinase family member 4 / Q86YV6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p25.2
Gene start: 2663629
Gene end: 2750966
  
Corresponding Affymetrix probe sets: 1556136_at (Human Genome U133 Plus 2.0 Array)   1561503_at (Human Genome U133 Plus 2.0 Array)   1561504_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000274643
Ensembl peptide - ENSP00000494309
NCBI entrez gene - 340156     See in Manteia.
RefSeq - XM_017010819
RefSeq - NM_001012418
RefSeq - NM_001347872
RefSeq - XM_005249079
RefSeq - XM_006715082
RefSeq - XM_011514567
RefSeq - XM_005249078
RefSeq Peptide - NP_001334801
RefSeq Peptide - NP_001012418
swissprot - Q86YV6
Ensembl - ENSG00000145949
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mylk4aENSDARG00000091260Danio rerio
 mylk4bENSDARG00000055412Danio rerio
 MYLK4ENSGALG00000012845Gallus gallus
 Mylk4ENSMUSG00000044951Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MYLK3 / Q32MK0 / myosin light chain kinase 3ENSG0000014079558
MYLK2 / Q9H1R3 / myosin light chain kinase 2ENSG0000010130650
MYLK / Q15746 / myosin light chain kinaseENSG0000006553443
DAPK2 / Q9UIK4 / death associated protein kinase 2ENSG0000003566433
DAPK1 / P53355 / death associated protein kinase 1ENSG0000019673032
SPEG / Q15772 / SPEG complex locusENSG0000007219530
Q9UEE5 / STK17A / serine/threonine kinase 17aENSG0000016454330
DAPK3 / O43293 / death associated protein kinase 3ENSG0000016765730
O94768 / STK17B / serine/threonine kinase 17bENSG0000008132029


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005622 intracellular IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004687 myosin light chain kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr