ENSG00000035664


Homo sapiens

Features
Gene ID: ENSG00000035664
  
Biological name :DAPK2
  
Synonyms : DAPK2 / death associated protein kinase 2 / Q9UIK4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q22.31
Gene start: 63907036
Gene end: 64072033
  
Corresponding Affymetrix probe sets: 206324_s_at (Human Genome U133 Plus 2.0 Array)   215184_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453639
Ensembl peptide - ENSP00000453284
Ensembl peptide - ENSP00000484390
Ensembl peptide - ENSP00000261891
Ensembl peptide - ENSP00000408277
Ensembl peptide - ENSP00000452970
Ensembl peptide - ENSP00000453101
Ensembl peptide - ENSP00000453235
NCBI entrez gene - 23604     See in Manteia.
OMIM - 616567
RefSeq - XM_017022051
RefSeq - XM_017022044
RefSeq - XM_017022045
RefSeq - XM_017022046
RefSeq - XM_017022047
RefSeq - XM_017022048
RefSeq - XM_017022049
RefSeq - XM_017022050
RefSeq - NM_014326
RefSeq - XM_011521413
RefSeq - XM_011521414
RefSeq - XM_011521415
RefSeq - XM_011521416
RefSeq - XM_011521417
RefSeq - XM_011521421
RefSeq - XM_017022043
RefSeq Peptide - NP_055141
swissprot - H0YL86
swissprot - H0YLP5
swissprot - H0YKW8
swissprot - A0A024R603
swissprot - Q9UIK4
swissprot - H0YMK1
Ensembl - ENSG00000035664
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dapk2aENSDARG00000061096Danio rerio
 dapk2bENSDARG00000103666Danio rerio
 DAPK2ENSGALG00000003336Gallus gallus
 Dapk2ENSMUSG00000032380Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DAPK1 / P53355 / death associated protein kinase 1ENSG0000019673062
DAPK3 / O43293 / death associated protein kinase 3ENSG0000016765761
MYLK / Q15746 / myosin light chain kinaseENSG0000006553438
O94768 / STK17B / serine/threonine kinase 17bENSG0000008132034
Q9UEE5 / STK17A / serine/threonine kinase 17aENSG0000016454334
MYLK4 / Q86YV6 / myosin light chain kinase family member 4ENSG0000014594934
MYLK3 / Q32MK0 / myosin light chain kinase 3ENSG0000014079534
MYLK2 / Q9H1R3 / myosin light chain kinase 2ENSG0000010130630
SPEG / Q15772 / SPEG complex locusENSG0000007219529


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0010506 regulation of autophagy TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043276 anoikis IMP
 biological_processGO:0046777 protein autophosphorylation TAS
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis IMP
 biological_processGO:1990266 neutrophil migration IEA
 biological_processGO:2000424 positive regulation of eosinophil chemotaxis IMP
 biological_processGO:2001242 regulation of intrinsic apoptotic signaling pathway IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0034423 autophagosome lumen IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
via Dependence Receptors in the absence of ligand


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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