ENSG00000147485


Homo sapiens

Features
Gene ID: ENSG00000147485
  
Biological name :PXDNL
  
Synonyms : A1KZ92 / peroxidasin like / PXDNL
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q11.23
Gene start: 51319578
Gene end: 51809445
  
Corresponding Affymetrix probe sets: 241942_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000429855
Ensembl peptide - ENSP00000348645
Ensembl peptide - ENSP00000428114
NCBI entrez gene - 137902     See in Manteia.
OMIM - 615904
RefSeq - XM_017013041
RefSeq - XM_011517456
RefSeq - XM_011517457
RefSeq - XM_011517458
RefSeq - XM_011517459
RefSeq - NM_144651
RefSeq - XM_005251168
RefSeq - XM_006716420
RefSeq Peptide - NP_653252
swissprot - H0YAV0
swissprot - K4DIA6
swissprot - A1KZ92
Ensembl - ENSG00000147485
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PXDN / Q92626 / peroxidasinENSG0000013050860
TPO / P07202 / thyroid peroxidaseENSG0000011570520
EPX / P11678 / eosinophil peroxidaseENSG0000012105319
MPO / P05164 / myeloperoxidaseENSG0000000538118
LPO / P22079 / lactoperoxidaseENSG0000016741917


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001007  VWFC domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR010255  Haem peroxidase
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR019791  Haem peroxidase, animal type
 IPR029610  Peroxidasin-like protein
 IPR032675  Leucine-rich repeat domain superfamily
 IPR034824  Peroxidasin, peroxidase domain
 IPR036179  Immunoglobulin-like domain superfamily
 IPR037120  Haem peroxidase domain superfamily, animal type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0042744 hydrogen peroxide catabolic process ISS
 biological_processGO:0055114 oxidation-reduction process ISS
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0004601 peroxidase activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0020037 heme binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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