ENSG00000148300


Homo sapiens

Features
Gene ID: ENSG00000148300
  
Biological name :REXO4
  
Synonyms : Q9GZR2 / REX4 homolog, 3-5 exonuclease / REXO4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.2
Gene start: 133406059
Gene end: 133418096
  
Corresponding Affymetrix probe sets: 218767_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391534
Ensembl peptide - ENSP00000394229
Ensembl peptide - ENSP00000361003
Ensembl peptide - ENSP00000361010
NCBI entrez gene - 57109     See in Manteia.
OMIM - 602930
RefSeq - NM_001279349
RefSeq - NM_001279350
RefSeq - NM_001279351
RefSeq - NM_020385
RefSeq Peptide - NP_001266279
RefSeq Peptide - NP_001266278
RefSeq Peptide - NP_065118
RefSeq Peptide - NP_001266280
swissprot - Q9GZR2
swissprot - A0A0C4DG31
swissprot - A0A0C4DG22
Ensembl - ENSG00000148300
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rexo4ENSDARG00000088619Danio rerio
 REXO4ENSGALG00000030609Gallus gallus
 Rexo4ENSMUSG00000052406Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H9L3 / ISG20L2 / interferon stimulated exonuclease gene 20 like 2ENSG0000014331922
AEN / Q8WTP8 / apoptosis enhancing nucleaseENSG0000018102620
ISG20 / Q96AZ6 / interferon stimulated exonuclease gene 20ENSG0000017218315


Protein motifs (from Interpro)
Interpro ID Name
 IPR012337  Ribonuclease H-like superfamily
 IPR013520  Exonuclease, RNase T/DNA polymerase III
 IPR036397  Ribonuclease H superfamily
 IPR037431  RNA exonuclease 4, DEDDh 3"-5" exonuclease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006364 rRNA processing IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0008408 3"-5" exonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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