ENSG00000151014


Homo sapiens

Features
Gene ID: ENSG00000151014
  
Biological name :NOCT
  
Synonyms : NOCT / nocturnin / Q9UK39
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q31.1
Gene start: 139015789
Gene end: 139045939
  
Corresponding Affymetrix probe sets: 1554283_at (Human Genome U133 Plus 2.0 Array)   220671_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000280614
Ensembl peptide - ENSP00000486546
NCBI entrez gene - 25819     See in Manteia.
OMIM - 608468
RefSeq - NM_012118
RefSeq Peptide - NP_036250
swissprot - Q8WTX0
swissprot - Q9UK39
Ensembl - ENSG00000151014
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 noctaENSDARG00000077726Danio rerio
 noctbENSDARG00000078525Danio rerio
 NOCTENSGALG00000032957Gallus gallus
 NoctENSMUSG00000023087Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANGEL1 / Q9UNK9 / angel homolog 1ENSG0000001352326
PDE12 / Q6L8Q7 / phosphodiesterase 12ENSG0000017484025
CNOT6 / Q9ULM6 / CCR4-NOT transcription complex subunit 6ENSG0000011330024
CNOT6L / Q96LI5 / CCR4-NOT transcription complex subunit 6 likeENSG0000013876724
ANGEL2 / Q5VTE6 / angel homolog 2ENSG0000017460624


Protein motifs (from Interpro)
Interpro ID Name
 IPR005135  Endonuclease/exonuclease/phosphatase
 IPR034965  Nocturnin, deadenylase domain
 IPR036691  Endonuclease/exonuclease/phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007623 circadian rhythm TAS
 biological_processGO:0009991 response to extracellular stimulus IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032922 circadian regulation of gene expression IEA
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly IEA
 biological_processGO:0042752 regulation of circadian rhythm IEA
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 biological_processGO:0045668 negative regulation of osteoblast differentiation IEA
 biological_processGO:0045995 regulation of embryonic development IEA
 biological_processGO:0048255 mRNA stabilization IEA
 biological_processGO:0048511 rhythmic process IEA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
BMAL1:CLOCK,NPAS2 activates circadian gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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