ENSG00000152520


Homo sapiens

Features
Gene ID: ENSG00000152520
  
Biological name :PAN3
  
Synonyms : PAN3 / PAN3 poly(A) specific ribonuclease subunit / Q58A45
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q12.2
Gene start: 28138506
Gene end: 28295335
  
Corresponding Affymetrix probe sets: 225563_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000382522
Ensembl peptide - ENSP00000370345
NCBI entrez gene - 255967     See in Manteia.
OMIM - 617448
RefSeq - XM_017020533
RefSeq - NM_175854
RefSeq - XM_017020530
RefSeq - XM_017020531
RefSeq - XM_017020532
RefSeq - XM_005266332
RefSeq - XM_005266333
RefSeq - XM_005266334
RefSeq - XM_011535032
RefSeq - XM_011535033
RefSeq - XM_011535034
RefSeq - XM_017020528
RefSeq - XM_017020529
RefSeq Peptide - NP_787050
swissprot - Q58A45
swissprot - A0A0C4DFZ9
Ensembl - ENSG00000152520
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pan3ENSDARG00000031637Danio rerio
 PAN3ENSGALG00000017092Gallus gallus
 Pan3ENSMUSG00000029647Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR030844  PAN2-PAN3 deadenylation complex subunit PAN3
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
 biological_processGO:0000289 nuclear-transcribed mRNA poly(A) tail shortening IEA
 biological_processGO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006605 protein targeting IEA
 biological_processGO:0010606 positive regulation of cytoplasmic mRNA processing body assembly IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0000932 P-body IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031251 PAN complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity IDA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Deadenylation of mRNA


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000135473 PAN2 / Q504Q3 / PAN2 poly(A) specific ribonuclease subunit  / complex






 

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