ENSG00000155660


Homo sapiens

Features
Gene ID: ENSG00000155660
  
Biological name :PDIA4
  
Synonyms : P13667 / PDIA4 / protein disulfide isomerase family A member 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q36.1
Gene start: 149003062
Gene end: 149028641
  
Corresponding Affymetrix probe sets: 208658_at (Human Genome U133 Plus 2.0 Array)   211048_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000286091
Ensembl peptide - ENSP00000408628
NCBI entrez gene - 9601     See in Manteia.
RefSeq - NM_004911
RefSeq - XM_006716185
RefSeq Peptide - NP_004902
swissprot - C9JMN9
swissprot - A0A090N8Y2
swissprot - P13667
Ensembl - ENSG00000155660
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdia4ENSDARG00000018491Danio rerio
 PDIA4ENSGALG00000043006Gallus gallus
 Pdia4ENSMUSG00000025823Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDIA3 / P30101 / protein disulfide isomerase family A member 3ENSG0000016700431
P4HB / P07237 / prolyl 4-hydroxylase subunit betaENSG0000018562425
PDIA2 / Q13087 / protein disulfide isomerase family A member 2ENSG0000018561524
PDILT / Q8N807 / protein disulfide isomerase like, testis expressedENSG0000016934018
ERP44 / Q9BS26 / endoplasmic reticulum protein 44ENSG0000002331814
TMX3 / Q96JJ7 / thioredoxin related transmembrane protein 3ENSG0000016647914
ERP27 / Q96DN0 / endoplasmic reticulum protein 27ENSG000001390556


Protein motifs (from Interpro)
Interpro ID Name
 IPR005788  Disulphide isomerase
 IPR005792  Protein disulphide isomerase
 IPR013766  Thioredoxin domain
 IPR017068  Protein disulphide-isomerase A4
 IPR017937  Thioredoxin, conserved site
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IBA
 biological_processGO:0009306 protein secretion TAS
 biological_processGO:0034976 response to endoplasmic reticulum stress IBA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0061077 chaperone-mediated protein folding ISS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0042470 melanosome IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003756 protein disulfide isomerase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015037 peptide disulfide oxidoreductase activity IDA
 molecular_functionGO:0016853 isomerase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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