ENSG00000166479


Homo sapiens

Features
Gene ID: ENSG00000166479
  
Biological name :TMX3
  
Synonyms : Q96JJ7 / thioredoxin related transmembrane protein 3 / TMX3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: q22.1
Gene start: 68673688
Gene end: 68715298
  
Corresponding Affymetrix probe sets: 1552822_at (Human Genome U133 Plus 2.0 Array)   225302_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000457262
Ensembl peptide - ENSP00000457074
Ensembl peptide - ENSP00000458132
Ensembl peptide - ENSP00000299608
Ensembl peptide - ENSP00000402605
Ensembl peptide - ENSP00000455234
Ensembl peptide - ENSP00000456453
Ensembl peptide - ENSP00000456587
NCBI entrez gene - 54495     See in Manteia.
OMIM - 616102
RefSeq - XM_011526035
RefSeq - NM_019022
RefSeq - XM_005266714
RefSeq - XM_011526033
RefSeq - XM_011526034
RefSeq Peptide - NP_061895
RefSeq Peptide - NP_001337441
swissprot - H3BPB3
swissprot - H3BRY0
swissprot - H3BT89
swissprot - B4DIE3
swissprot - H3BVI1
swissprot - Q96JJ7
Ensembl - ENSG00000166479
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmx3aENSDARG00000038894Danio rerio
 tmx3bENSDARG00000088466Danio rerio
 TMX3ENSGALG00000013757Gallus gallus
 Tmx3ENSMUSG00000024614Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P4HB / P07237 / prolyl 4-hydroxylase subunit betaENSG0000018562421
PDIA4 / P13667 / protein disulfide isomerase family A member 4ENSG0000015566019
PDIA3 / P30101 / protein disulfide isomerase family A member 3ENSG0000016700417
PDIA2 / Q13087 / protein disulfide isomerase family A member 2ENSG0000018561517
ERP44 / Q9BS26 / endoplasmic reticulum protein 44ENSG0000002331815
PDILT / Q8N807 / protein disulfide isomerase like, testis expressedENSG0000016934015
ERP27 / Q96DN0 / endoplasmic reticulum protein 27ENSG000001390558


Protein motifs (from Interpro)
Interpro ID Name
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0006457 protein folding IBA
 biological_processGO:0018171 peptidyl-cysteine oxidation IDA
 biological_processGO:0034976 response to endoplasmic reticulum stress IBA
 biological_processGO:0045454 cell redox homeostasis IEA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031092 platelet alpha granule membrane TAS
 molecular_functionGO:0003756 protein disulfide isomerase activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0016972 thiol oxidase activity IDA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr