ENSMUSG00000024614


Mus musculus

Features
Gene ID: ENSMUSG00000024614
  
Biological name :Tmx3
  
Synonyms : Protein disulfide-isomerase TMX3 / Q8BXZ1 / Tmx3
  
Possible biological names infered from orthology : Q96JJ7 / thioredoxin related transmembrane protein 3
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: E4
Gene start: 90510154
Gene end: 90543267
  
Corresponding Affymetrix probe sets: 10457183 (MoGene1.0st)   1419925_s_at (Mouse Genome 430 2.0 Array)   1419926_at (Mouse Genome 430 2.0 Array)   1430995_at (Mouse Genome 430 2.0 Array)   1440279_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025515
NCBI entrez gene - 67988     See in Manteia.
MGI - MGI:2442418
RefSeq - NM_198295
RefSeq Peptide - NP_938037
swissprot - Q8BXZ1
Ensembl - ENSMUSG00000024614
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmx3aENSDARG00000038894Danio rerio
 tmx3bENSDARG00000088466Danio rerio
 TMX3ENSGALG00000013757Gallus gallus
 TMX3ENSG00000166479Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P4hb / P09103 / prolyl 4-hydroxylase, beta polypeptide / P07237* / prolyl 4-hydroxylase subunit beta*ENSMUSG0000002513020
Pdia3 / P27773 / Protein disulfide-isomerase A3 / P30101* / protein disulfide isomerase family A member 3*ENSMUSG0000002724818
Pdia4 / protein disulfide isomerase family A member 4 / P13667*ENSMUSG0000002582318
Pdia2 / D3Z6P0 / Protein disulfide-isomerase A2 / Q13087* / protein disulfide isomerase family A member 2*ENSMUSG0000002418417
Pdilt / Q9DAN1 / Protein disulfide-isomerase-like protein of the testis / Q8N807* / protein disulfide isomerase like, testis expressed*ENSMUSG0000003096814
Erp44 / Q9D1Q6 / Endoplasmic reticulum resident protein 44 / Q9BS26* / endoplasmic reticulum protein 44*ENSMUSG0000002834314
Erp27 / Q9D8U3 / Endoplasmic reticulum resident protein 27 / Q96DN0* / endoplasmic reticulum protein 27*ENSMUSG000000302197


Protein motifs (from Interpro)
Interpro ID Name
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IBA
 biological_processGO:0018171 peptidyl-cysteine oxidation IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IBA
 biological_processGO:0045454 cell redox homeostasis IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISO
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003756 protein disulfide isomerase activity IBA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0016972 thiol oxidase activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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