ENSMUSG00000024184


Mus musculus

Features
Gene ID: ENSMUSG00000024184
  
Biological name :Pdia2
  
Synonyms : D3Z6P0 / Pdia2 / Protein disulfide-isomerase A2
  
Possible biological names infered from orthology : protein disulfide isomerase family A member 2 / Q13087
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.3
Gene start: 26195999
Gene end: 26199087
  
Corresponding Affymetrix probe sets: 10449245 (MoGene1.0st)   1428952_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000035584
Ensembl peptide - ENSMUSP00000114080
Ensembl peptide - ENSMUSP00000115267
Ensembl peptide - ENSMUSP00000116340
NCBI entrez gene - 69191     See in Manteia.
MGI - MGI:1916441
RefSeq - XM_006524872
RefSeq - NM_001081070
RefSeq Peptide - NP_001074539
swissprot - F6Q519
swissprot - D3Z6P0
swissprot - F6S5U2
Ensembl - ENSMUSG00000024184
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdia2ENSDARG00000018263Danio rerio
 PDIA2ENSGALG00000040070Gallus gallus
 PDIA2ENSG00000185615Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P4hb / P09103 / prolyl 4-hydroxylase, beta polypeptide / P07237* / prolyl 4-hydroxylase subunit beta*ENSMUSG0000002513044
Pdia4 / protein disulfide isomerase family A member 4 / P13667*ENSMUSG0000002582330
Pdilt / Q9DAN1 / Protein disulfide-isomerase-like protein of the testis / Q8N807* / protein disulfide isomerase like, testis expressed*ENSMUSG0000003096829
Pdia3 / P27773 / Protein disulfide-isomerase A3 / P30101* / protein disulfide isomerase family A member 3*ENSMUSG0000002724827
Erp44 / Q9D1Q6 / Endoplasmic reticulum resident protein 44 / Q9BS26* / endoplasmic reticulum protein 44*ENSMUSG0000002834315
Erp27 / Q9D8U3 / Endoplasmic reticulum resident protein 27 / Q96DN0* / endoplasmic reticulum protein 27*ENSMUSG0000003021915
Tmx3 / Q8BXZ1 / Protein disulfide-isomerase TMX3 / Q96JJ7* / thioredoxin related transmembrane protein 3*ENSMUSG0000002461414


Protein motifs (from Interpro)
Interpro ID Name
 IPR005788  Disulphide isomerase
 IPR005792  Protein disulphide isomerase
 IPR013766  Thioredoxin domain
 IPR017937  Thioredoxin, conserved site
 IPR036249  Thioredoxin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IBA
 biological_processGO:0019511 peptidyl-proline hydroxylation IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IBA
 biological_processGO:0045454 cell redox homeostasis IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway IBA
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005788 endoplasmic reticulum lumen IEA
 molecular_functionGO:0003756 protein disulfide isomerase activity TAS
 molecular_functionGO:0005496 steroid binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015037 peptide disulfide oxidoreductase activity ISO
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0031545 peptidyl-proline 4-dioxygenase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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