ENSG00000156463


Homo sapiens

Features
Gene ID: ENSG00000156463
  
Biological name :SH3RF2
  
Synonyms : Q8TEC5 / SH3 domain containing ring finger 2 / SH3RF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q32
Gene start: 145936579
Gene end: 146081791
  
Corresponding Affymetrix probe sets: 228892_at (Human Genome U133 Plus 2.0 Array)   235768_at (Human Genome U133 Plus 2.0 Array)   238827_at (Human Genome U133 Plus 2.0 Array)   243582_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352028
Ensembl peptide - ENSP00000424497
NCBI entrez gene - 153769     See in Manteia.
OMIM - 613377
RefSeq - XM_017009136
RefSeq - NM_152550
RefSeq - XM_011537568
RefSeq - XM_011537569
RefSeq - XM_005268380
RefSeq - XM_006714757
RefSeq - XM_011537567
RefSeq Peptide - NP_689763
swissprot - Q8TEC5
Ensembl - ENSG00000156463
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sh3rf2ENSDARG00000101178Danio rerio
 SH3RF2ENSGALG00000043904Gallus gallus
 Q8BZT2ENSMUSG00000057719Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7Z6J0 / SH3RF1 / SH3 domain containing ring finger 1ENSG0000015444734
Q8TEJ3 / SH3RF3 / SH3 domain containing ring finger 3ENSG0000017298534
Q9BX66 / SORBS1 / sorbin and SH3 domain containing 1ENSG0000009563715
O60504 / SORBS3 / sorbin and SH3 domain containing 3ENSG0000012089612
O94875 / SORBS2 / sorbin and SH3 domain containing 2ENSG0000015455612
Q5HYK7 / SH3D19 / SH3 domain containing 19ENSG000001096869


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif
 IPR028511  Putative E3 ubiquitin-protein ligase SH3RF2
 IPR035792  Putative E3 ubiquitin-protein ligase SH3RF2, first SH3 domain
 IPR035794  Putative E3 ubiquitin-protein ligase SH3RF2, second SH3 domain
 IPR035822  SH3RF2, third SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010923 negative regulation of phosphatase activity IDA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 molecular_functionGO:0004864 protein phosphatase inhibitor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008157 protein phosphatase 1 binding IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019902 phosphatase binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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