ENSG00000154556


Homo sapiens

Features
Gene ID: ENSG00000154556
  
Biological name :SORBS2
  
Synonyms : O94875 / sorbin and SH3 domain containing 2 / SORBS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q35.1
Gene start: 185585444
Gene end: 185956652
  
Corresponding Affymetrix probe sets: 1555472_at (Human Genome U133 Plus 2.0 Array)   1558815_at (Human Genome U133 Plus 2.0 Array)   204288_s_at (Human Genome U133 Plus 2.0 Array)   220858_at (Human Genome U133 Plus 2.0 Array)   225728_at (Human Genome U133 Plus 2.0 Array)   233720_at (Human Genome U133 Plus 2.0 Array)   237285_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396183
Ensembl peptide - ENSP00000397262
Ensembl peptide - ENSP00000416464
Ensembl peptide - ENSP00000415680
Ensembl peptide - ENSP00000415637
Ensembl peptide - ENSP00000415392
Ensembl peptide - ENSP00000415166
Ensembl peptide - ENSP00000412447
Ensembl peptide - ENSP00000410967
Ensembl peptide - ENSP00000410483
Ensembl peptide - ENSP00000410233
Ensembl peptide - ENSP00000409158
Ensembl peptide - ENSP00000408909
Ensembl peptide - ENSP00000408504
Ensembl peptide - ENSP00000407006
Ensembl peptide - ENSP00000405646
Ensembl peptide - ENSP00000405432
Ensembl peptide - ENSP00000405349
Ensembl peptide - ENSP00000405314
Ensembl peptide - ENSP00000405092
Ensembl peptide - ENSP00000404430
Ensembl peptide - ENSP00000403417
Ensembl peptide - ENSP00000402328
Ensembl peptide - ENSP00000401818
Ensembl peptide - ENSP00000399048
Ensembl peptide - ENSP00000398335
Ensembl peptide - ENSP00000397664
Ensembl peptide - ENSP00000397482
Ensembl peptide - ENSP00000284776
Ensembl peptide - ENSP00000321983
Ensembl peptide - ENSP00000322182
Ensembl peptide - ENSP00000347852
Ensembl peptide - ENSP00000377158
Ensembl peptide - ENSP00000377162
Ensembl peptide - ENSP00000389829
Ensembl peptide - ENSP00000389995
Ensembl peptide - ENSP00000390162
Ensembl peptide - ENSP00000391940
Ensembl peptide - ENSP00000393258
Ensembl peptide - ENSP00000396008
NCBI entrez gene - 8470     See in Manteia.
OMIM - 616349
RefSeq - XM_017008775
RefSeq - NM_001145673
RefSeq - NM_001145674
RefSeq - NM_001145675
RefSeq - NM_001270771
RefSeq - NM_003603
RefSeq - NM_021069
RefSeq - XM_005263307
RefSeq - XM_005263308
RefSeq - XM_005263310
RefSeq - XM_005263311
RefSeq - XM_005263312
RefSeq - XM_005263313
RefSeq - XM_006714388
RefSeq - XM_006714390
RefSeq - XM_017008741
RefSeq - XM_017008748
RefSeq - XM_017008750
RefSeq - XM_017008751
RefSeq - XM_017008752
RefSeq - XM_017008753
RefSeq - XM_017008754
RefSeq - XM_017008755
RefSeq - XM_017008756
RefSeq - XM_017008757
RefSeq - XM_017008758
RefSeq - XM_017008759
RefSeq - XM_017008760
RefSeq - XM_017008762
RefSeq - XM_017008763
RefSeq - XM_017008764
RefSeq - XM_017008765
RefSeq - XM_017008766
RefSeq - XM_017008767
RefSeq - XM_017008768
RefSeq - XM_017008769
RefSeq - XM_017008770
RefSeq - XM_017008771
RefSeq - XM_017008772
RefSeq - XM_017008773
RefSeq - XM_017008774
RefSeq - NM_001145670
RefSeq - NM_001145671
RefSeq - NM_001145672
RefSeq Peptide - NP_001139146
RefSeq Peptide - NP_001139147
RefSeq Peptide - NP_001257700
RefSeq Peptide - NP_003594
RefSeq Peptide - NP_066547
RefSeq Peptide - NP_001139144
RefSeq Peptide - NP_001139145
RefSeq Peptide - NP_001139142
RefSeq Peptide - NP_001139143
swissprot - C9JDX2
swissprot - C9JC90
swissprot - C9JBR8
swissprot - C9JBB0
swissprot - C9J9D3
swissprot - C9J8E3
swissprot - C9J7Q5
swissprot - C9J620
swissprot - C9J4Z9
swissprot - C9J4K2
swissprot - C9J3W4
swissprot - C9JWC3
swissprot - C9J348
swissprot - C9IZT7
swissprot - C9IZ89
swissprot - A0A1D5RMN3
swissprot - H7BXR3
swissprot - H7BZK1
swissprot - H7BZX1
swissprot - H7C1R7
swissprot - O94875
swissprot - C9JZ60
swissprot - C9J372
swissprot - C9JN77
swissprot - C9JM25
swissprot - C9JLD6
swissprot - C9JL62
swissprot - C9JI79
swissprot - C9JG84
swissprot - C9JFS9
swissprot - C9JEA9
Ensembl - ENSG00000154556
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sorbs2aENSDARG00000003046Danio rerio
 sorbs2bENSDARG00000061603Danio rerio
 SORBS2ENSGALG00000013427Gallus gallus
 Q3UTJ2ENSMUSG00000031626Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BX66 / SORBS1 / sorbin and SH3 domain containing 1ENSG0000009563724
O60504 / SORBS3 / sorbin and SH3 domain containing 3ENSG0000012089616
Q5HYK7 / SH3D19 / SH3 domain containing 19ENSG0000010968611
Q7Z6J0 / SH3RF1 / SH3 domain containing ring finger 1ENSG000001544479
Q8TEJ3 / SH3RF3 / SH3 domain containing ring finger 3ENSG000001729858
Q8TEC5 / SH3RF2 / SH3 domain containing ring finger 2ENSG000001564637


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR003127  SoHo domain
 IPR013087  Zinc finger C2H2-type
 IPR028506  Sorbin and SH3 domain-containing protein
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007015 actin filament organization IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0061049 cell growth involved in cardiac muscle cell development ISS
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0015629 actin cytoskeleton TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030018 Z disc NAS
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005200 structural constituent of cytoskeleton TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008093 cytoskeletal adaptor activity TAS
 molecular_functionGO:0008307 structural constituent of muscle TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr