ENSG00000156735


Homo sapiens

Features
Gene ID: ENSG00000156735
  
Biological name :BAG4
  
Synonyms : BAG4 / BCL2 associated athanogene 4 / O95429
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p11.23
Gene start: 38176533
Gene end: 38213301
  
Corresponding Affymetrix probe sets: 219624_at (Human Genome U133 Plus 2.0 Array)   222909_s_at (Human Genome U133 Plus 2.0 Array)   228189_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393298
Ensembl peptide - ENSP00000287322
Ensembl peptide - ENSP00000430250
NCBI entrez gene - 9530     See in Manteia.
OMIM - 603884
RefSeq - NM_004874
RefSeq - NM_001204878
RefSeq Peptide - NP_001191807
RefSeq Peptide - NP_004865
swissprot - O95429
swissprot - H0YBT1
Ensembl - ENSG00000156735
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bag4ENSDARG00000043179Danio rerio
 BAG4ENSGALG00000003254Gallus gallus
 Bag4ENSMUSG00000037316Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BAG3 / O95817 / BCL2 associated athanogene 3ENSG0000015192921
BAG5 / Q9UL15 / BCL2 associated athanogene 5ENSG0000016617014


Protein motifs (from Interpro)
Interpro ID Name
 IPR003103  BAG domain
 IPR036533  BAG domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0010763 positive regulation of fibroblast migration IEA
 biological_processGO:0030838 positive regulation of actin filament polymerization IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0045785 positive regulation of cell adhesion IEA
 biological_processGO:0051291 protein heterooligomerization IEA
 biological_processGO:0051496 positive regulation of stress fiber assembly IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IEA
 biological_processGO:0072659 protein localization to plasma membrane IEA
 biological_processGO:0090367 negative regulation of mRNA modification IEA
 biological_processGO:0097178 ruffle assembly IEA
 biological_processGO:1900034 regulation of cellular response to heat TAS
 biological_processGO:1903215 negative regulation of protein targeting to mitochondrion IMP
 biological_processGO:2001145 negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0000774 adenyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005057 obsolete signal transducer activity, downstream of receptor TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0051087 chaperone binding IEA


Pathways (from Reactome)
Pathway description
Regulation of HSF1-mediated heat shock response
Signaling by FGFR1 in disease
TNF signaling
Signaling by plasma membrane FGFR1 fusions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000156735 BAG4 / O95429 / BCL2 associated athanogene 4  / complex
 ENSG00000067182 P19438 / TNFRSF1A / TNF receptor superfamily member 1A  / complex
 ENSG00000232810 TNF / P01375 / tumor necrosis factor  / reaction






 

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