ENSG00000159674


Homo sapiens

Features
Gene ID: ENSG00000159674
  
Biological name :SPON2
  
Synonyms : Q9BUD6 / SPON2 / spondin 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p16.3
Gene start: 1166932
Gene end: 1208962
  
Corresponding Affymetrix probe sets: 1569496_s_at (Human Genome U133 Plus 2.0 Array)   218638_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000394832
Ensembl peptide - ENSP00000483599
Ensembl peptide - ENSP00000425871
Ensembl peptide - ENSP00000424542
Ensembl peptide - ENSP00000423414
Ensembl peptide - ENSP00000422516
Ensembl peptide - ENSP00000421858
Ensembl peptide - ENSP00000421634
Ensembl peptide - ENSP00000421379
Ensembl peptide - ENSP00000290902
NCBI entrez gene - 10417     See in Manteia.
OMIM - 605918
RefSeq - NM_001199021
RefSeq - NM_012445
RefSeq - NM_001128325
RefSeq Peptide - NP_001121797
RefSeq Peptide - NP_001185950
RefSeq Peptide - NP_036577
swissprot - D6RIH5
swissprot - Q9BUD6
swissprot - D6RFY9
swissprot - D6REX2
swissprot - D6RBY3
swissprot - D6RB12
swissprot - D6RA41
swissprot - A0A1Y8ELY7
Ensembl - ENSG00000159674
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spon2bENSDARG00000002732Danio rerio
 SPON2ENSGALG00000038433Gallus gallus
 Spon2ENSMUSG00000037379Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPON1 / Q9HCB6 / spondin 1ENSG0000026265533


Protein motifs (from Interpro)
Interpro ID Name
 IPR000884  Thrombospondin type-1 (TSP1) repeat
 IPR009465  Spondin, N-terminal
 IPR036383  Thrombospondin type-1 (TSP1) repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002448 mast cell mediated immunity IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0008228 opsonization IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production IEA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IEA
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0043152 induction of bacterial agglutination IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050832 defense response to fungus IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0060907 positive regulation of macrophage cytokine production IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001530 lipopolysaccharide binding IEA
 molecular_functionGO:0003823 antigen binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Defective B3GALTL causes Peters-plus syndrome (PpS)
O-glycosylation of TSR domain-containing proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr