ENSG00000161547


Homo sapiens

Features
Gene ID: ENSG00000161547
  
Biological name :SRSF2
  
Synonyms : Q01130 / serine and arginine rich splicing factor 2 / SRSF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.1
Gene start: 76734115
Gene end: 76737374
  
Corresponding Affymetrix probe sets: 200753_x_at (Human Genome U133 Plus 2.0 Array)   200754_x_at (Human Genome U133 Plus 2.0 Array)   214882_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000441780
Ensembl peptide - ENSP00000462425
Ensembl peptide - ENSP00000463317
Ensembl peptide - ENSP00000350877
Ensembl peptide - ENSP00000353089
Ensembl peptide - ENSP00000376276
Ensembl peptide - ENSP00000391278
NCBI entrez gene - 6427     See in Manteia.
OMIM - 600813
RefSeq - XM_017024942
RefSeq - NM_001195427
RefSeq - NM_003016
RefSeq Peptide - NP_001182356
RefSeq Peptide - NP_003007
swissprot - Q01130
swissprot - A0A024R8U5
swissprot - J3KP15
swissprot - J3QL05
Ensembl - ENSG00000161547
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srsf2aENSDARG00000057484Danio rerio
 srsf2bENSDARG00000103893Danio rerio
 Srsf2ENSMUSG00000034120Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SRSF8 / Q9BRL6 / serine and arginine rich splicing factor 8ENSG0000026346563
O75494 / SRSF10 / serine and arginine rich splicing factor 10ENSG0000018852940
Q8WXF0 / SRSF12 / serine and arginine rich splicing factor 12ENSG0000015454838


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR003954  RNA recognition motif domain, eukaryote
 IPR034893  Serine/arginine-rich splicing factor 2-like
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IEA
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome IEA
 biological_processGO:0000398 mRNA splicing, via spliceosome TAS
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing TAS
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0031124 mRNA 3"-end processing TAS
 biological_processGO:0033197 response to vitamin E IEA
 biological_processGO:0043484 regulation of RNA splicing IEA
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0035061 interchromatin granule IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003714 transcription corepressor activity NAS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005080 protein kinase C binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0036002 pre-mRNA binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
mRNA 3-end processing


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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