ENSG00000188529


Homo sapiens

Features
Gene ID: ENSG00000188529
  
Biological name :SRSF10
  
Synonyms : O75494 / serine and arginine rich splicing factor 10 / SRSF10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.11
Gene start: 23964804
Gene end: 23980927
  
Corresponding Affymetrix probe sets: 204299_at (Human Genome U133 Plus 2.0 Array)   206095_s_at (Human Genome U133 Plus 2.0 Array)   210178_x_at (Human Genome U133 Plus 2.0 Array)   213594_x_at (Human Genome U133 Plus 2.0 Array)   225348_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473291
Ensembl peptide - ENSP00000420195
Ensembl peptide - ENSP00000473293
Ensembl peptide - ENSP00000342913
Ensembl peptide - ENSP00000344149
Ensembl peptide - ENSP00000363576
Ensembl peptide - ENSP00000363577
Ensembl peptide - ENSP00000388991
Ensembl peptide - ENSP00000419813
NCBI entrez gene - 10772     See in Manteia.
OMIM - 605221
RefSeq - XM_017000102
RefSeq - NM_001191005
RefSeq - NM_001191006
RefSeq - NM_001191007
RefSeq - NM_001191009
RefSeq - NM_001300936
RefSeq - NM_001300937
RefSeq - NM_006625
RefSeq - NM_054016
RefSeq - XM_017000100
RefSeq - XM_017000101
RefSeq Peptide - NP_001177936
RefSeq Peptide - NP_001177938
RefSeq Peptide - NP_001287865
RefSeq Peptide - NP_001287866
RefSeq Peptide - NP_006616
RefSeq Peptide - NP_473357
RefSeq Peptide - NP_001177934
RefSeq Peptide - NP_001177935
swissprot - Q6IQ42
swissprot - R4GMP8
swissprot - A0A0S2Z504
swissprot - O75494
swissprot - Q5JRI1
Ensembl - ENSG00000188529
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srsf10bENSDARG00000086411Danio rerio
 SRSF10ENSGALG00000004133Gallus gallus
 Q9R0U0ENSMUSG00000028676Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WXF0 / SRSF12 / serine and arginine rich splicing factor 12ENSG0000015454852
SRSF2 / Q01130 / serine and arginine rich splicing factor 2ENSG0000016154734
SRSF8 / Q9BRL6 / serine and arginine rich splicing factor 8ENSG0000026346533


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR034476  Serine/arginine-rich splicing factor 10
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000244 spliceosomal tri-snRNP complex assembly NAS
 biological_processGO:0000375 RNA splicing, via transesterification reactions IDA
 biological_processGO:0000398 mRNA splicing, via spliceosome IDA
 biological_processGO:0006355 regulation of transcription, DNA-templated NAS
 biological_processGO:0006376 mRNA splice site selection IDA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006406 mRNA export from nucleus NAS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0016482 cytosolic transport IEA
 biological_processGO:0043484 regulation of RNA splicing IEA
 biological_processGO:0048024 regulation of mRNA splicing, via spliceosome IDA
 biological_processGO:0048025 negative regulation of mRNA splicing, via spliceosome IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0050733 RS domain binding NAS
 molecular_functionGO:0051082 unfolded protein binding NAS


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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