ENSG00000161849


Homo sapiens

Features
Gene ID: ENSG00000161849
  
Biological name :KRT84
  
Synonyms : keratin 84 / KRT84 / Q9NSB2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.13
Gene start: 52377812
Gene end: 52385652
  
Corresponding Affymetrix probe sets: 217031_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000257951
NCBI entrez gene - 3890     See in Manteia.
OMIM - 602766
RefSeq - NM_033045
RefSeq - XM_011538335
RefSeq Peptide - NP_149034
swissprot - Q9NSB2
Ensembl - ENSG00000161849
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000042769Gallus gallus
 Krt84ENSMUSG00000044294Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KRT85 / P78386 / keratin 85ENSG0000013544353
KRT82 / Q9NSB4 / keratin 82ENSG0000016185051
KRT81 / Q14533 / keratin 81ENSG0000020542650
KRT83 / P78385 / keratin 83ENSG0000017052350
KRT86 / O43790 / keratin 86ENSG0000017044249
KRT2 / P35908 / keratin 2ENSG0000017286743
KRT73 / Q86Y46 / keratin 73ENSG0000018604943
KRT77 / Q7Z794 / keratin 77ENSG0000018918241
KRT72 / Q14CN4 / keratin 72ENSG0000017048641
KRT74 / Q7RTS7 / keratin 74ENSG0000017048440
KRT78 / Q8N1N4 / keratin 78ENSG0000017042337
KRT80 / Q6KB66 / keratin 80ENSG0000016776731


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR003054  Keratin, type II
 IPR018039  Intermediate filament protein, conserved site
 IPR032444  Keratin type II head


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001942 hair follicle development NAS
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0031424 keratinization TAS
 biological_processGO:0035878 nail development NAS
 biological_processGO:0045616 regulation of keratinocyte differentiation IEA
 biological_processGO:0070268 cornification TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0045095 keratin filament IDA
 cellular_componentGO:0045111 intermediate filament cytoskeleton IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton NAS
 molecular_functionGO:0030280 structural constituent of epidermis IEA


Pathways (from Reactome)
Pathway description
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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