ENSG00000186049


Homo sapiens

Features
Gene ID: ENSG00000186049
  
Biological name :KRT73
  
Synonyms : keratin 73 / KRT73 / Q86Y46
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.13
Gene start: 52607570
Gene end: 52618559
  
Corresponding Affymetrix probe sets: 1553537_at (Human Genome U133 Plus 2.0 Array)   237507_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000307014
Ensembl peptide - ENSP00000449081
NCBI entrez gene - 319101     See in Manteia.
OMIM - 608247
RefSeq - XM_011538257
RefSeq - NM_175068
RefSeq Peptide - NP_778238
swissprot - Q86Y46
swissprot - H0YIC5
Ensembl - ENSG00000186049
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Krt73ENSMUSG00000063661Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KRT74 / Q7RTS7 / keratin 74ENSG0000017048473
KRT72 / Q14CN4 / keratin 72ENSG0000017048671
KRT2 / P35908 / keratin 2ENSG0000017286759
KRT77 / Q7Z794 / keratin 77ENSG0000018918256
KRT78 / Q8N1N4 / keratin 78ENSG0000017042349
KRT84 / Q9NSB2 / keratin 84ENSG0000016184948
KRT85 / P78386 / keratin 85ENSG0000013544345
KRT81 / Q14533 / keratin 81ENSG0000020542644
KRT82 / Q9NSB4 / keratin 82ENSG0000016185044
KRT83 / P78385 / keratin 83ENSG0000017052343
KRT86 / O43790 / keratin 86ENSG0000017044243
KRT80 / Q6KB66 / keratin 80ENSG0000016776733


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR003054  Keratin, type II
 IPR018039  Intermediate filament protein, conserved site
 IPR032444  Keratin type II head


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0031424 keratinization TAS
 biological_processGO:0070268 cornification TAS
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0045095 keratin filament IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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