ENSG00000163002


Homo sapiens

Features
Gene ID: ENSG00000163002
  
Biological name :NUP35
  
Synonyms : nucleoporin 35 / NUP35 / Q8NFH5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q32.1
Gene start: 183117513
Gene end: 183161680
  
Corresponding Affymetrix probe sets: 225470_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393130
Ensembl peptide - ENSP00000387305
Ensembl peptide - ENSP00000403819
Ensembl peptide - ENSP00000412554
Ensembl peptide - ENSP00000412311
Ensembl peptide - ENSP00000295119
Ensembl peptide - ENSP00000364066
NCBI entrez gene - 129401     See in Manteia.
OMIM - 608140
RefSeq - XM_017003308
RefSeq - NM_001287584
RefSeq - NM_001287585
RefSeq - NM_138285
RefSeq - XM_006712254
RefSeq - XM_011510576
RefSeq - XM_011510577
RefSeq Peptide - NP_001274514
RefSeq Peptide - NP_612142
RefSeq Peptide - NP_001274513
swissprot - F8WCF5
swissprot - F8WEL4
swissprot - C9IYQ7
swissprot - Q8NFH5
swissprot - C9JWU7
swissprot - C9JIY9
Ensembl - ENSG00000163002
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nup35ENSDARG00000012222Danio rerio
 ENSGALG00000002689Gallus gallus
 Gm4353ENSMUSG00000091900Mus musculus
 Nup35ENSMUSG00000026999Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007846  RNA-recognition motif (RRM) Nup35-type domain
 IPR017389  Nucleoporin, NUP53
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006110 regulation of glycolytic process TAS
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0006409 tRNA export from nucleus TAS
 biological_processGO:0006607 NLS-bearing protein import into nucleus IBA
 biological_processGO:0006913 nucleocytoplasmic transport IEA
 biological_processGO:0006999 nuclear pore organization IBA
 biological_processGO:0007077 mitotic nuclear envelope disassembly TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0016925 protein sumoylation TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0051028 mRNA transport IEA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0075733 intracellular transport of virus TAS
 biological_processGO:1900034 regulation of cellular response to heat TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope TAS
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005652 nuclear lamina IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0043657 host cell IEA
 cellular_componentGO:0044613 nuclear pore central transport channel IBA
 cellular_componentGO:0044615 nuclear pore nuclear basket IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding IBA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
tRNA processing in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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