ENSG00000163072


Homo sapiens

Features
Gene ID: ENSG00000163072
  
Biological name :NOSTRIN
  
Synonyms : nitric oxide synthase trafficking / NOSTRIN / Q8IVI9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q24.3
Gene start: 168786539
Gene end: 168865514
  
Corresponding Affymetrix probe sets: 226992_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000404413
Ensembl peptide - ENSP00000402140
Ensembl peptide - ENSP00000415337
Ensembl peptide - ENSP00000318921
Ensembl peptide - ENSP00000380390
Ensembl peptide - ENSP00000380392
Ensembl peptide - ENSP00000388597
Ensembl peptide - ENSP00000390383
Ensembl peptide - ENSP00000394051
NCBI entrez gene - 115677     See in Manteia.
OMIM - 607496
RefSeq - XM_017003280
RefSeq - NM_001171631
RefSeq - NM_001171632
RefSeq - NM_052946
RefSeq - XM_005246270
RefSeq - XM_006712233
RefSeq - XM_011510540
RefSeq - XM_017003278
RefSeq - XM_017003279
RefSeq - NM_001039724
RefSeq Peptide - NP_001165103
RefSeq Peptide - NP_443178
RefSeq Peptide - NP_001034813
RefSeq Peptide - NP_001165102
swissprot - Q8IVI9
swissprot - H7BZA6
swissprot - F8WCW8
swissprot - E9PDM0
Ensembl - ENSG00000163072
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nostrinENSDARG00000077866Danio rerio
 Q6WKZ7ENSMUSG00000034738Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR027267  AH/BAR domain superfamily
 IPR028535  Nostrin
 IPR031160  F-BAR domain
 IPR035656  Nostrin, SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036274  HR1 repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0050999 regulation of nitric-oxide synthase activity TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0030666 endocytic vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
NOSTRIN mediated eNOS trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164867 NOS3 / P29474 / nitric oxide synthase 3  / complex / reaction
 ENSG00000105974 CAV1 / Q03135 / caveolin 1  / complex / reaction
 ENSG00000106299 WASL / O00401 / Wiskott-Aldrich syndrome like  / complex / reaction
 ENSG00000079805 DNM2 / P50570 / dynamin 2  / complex / reaction
 ENSG00000163072 Q8IVI9 / NOSTRIN / nitric oxide synthase trafficking  / complex






 

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contact: otassy@igbmc.fr