ENSG00000163491


Homo sapiens

Features
Gene ID: ENSG00000163491
  
Biological name :NEK10
  
Synonyms : NEK10 / NIMA related kinase 10 / Q6ZWH5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p24.1
Gene start: 27110085
Gene end: 27369460
  
Corresponding Affymetrix probe sets: 237227_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395338
Ensembl peptide - ENSP00000395849
Ensembl peptide - ENSP00000412651
Ensembl peptide - ENSP00000295720
Ensembl peptide - ENSP00000343847
Ensembl peptide - ENSP00000373280
Ensembl peptide - ENSP00000373281
Ensembl peptide - ENSP00000392344
NCBI entrez gene - 152110     See in Manteia.
RefSeq - XM_017005774
RefSeq - XM_017005765
RefSeq - XM_017005766
RefSeq - XM_017005767
RefSeq - XM_017005768
RefSeq - XM_017005769
RefSeq - XM_017005770
RefSeq - XM_017005771
RefSeq - XM_017005772
RefSeq - XM_017005773
RefSeq - NM_001031741
RefSeq - NM_001304384
RefSeq - NM_152534
RefSeq - NM_199347
RefSeq - XM_006712997
RefSeq - XM_006712998
RefSeq - XM_006712999
RefSeq - XM_006713001
RefSeq - XM_006713002
RefSeq - XM_011533413
RefSeq - XM_011533414
RefSeq - XM_011533415
RefSeq - XM_017005761
RefSeq - XM_017005762
RefSeq - XM_017005763
RefSeq - XM_017005764
RefSeq Peptide - NP_001291313
RefSeq Peptide - NP_689747
RefSeq Peptide - NP_955379
RefSeq Peptide - NP_001026911
swissprot - C9JJN0
swissprot - Q6ZWH5
swissprot - H7C000
swissprot - H7C3L8
swissprot - A0A0A0MRY8
Ensembl - ENSG00000163491
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nek10ENSDARG00000025335Danio rerio
 ENSGALG00000040569Gallus gallus
 ENSGALG00000011322Gallus gallus
 Nek10ENSMUSG00000042567Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AURKA / O14965 / aurora kinase AENSG0000008758611
AURKB / Q96GD4 / aurora kinase BENSG000001789999
AURKC / Q9UQB9 / aurora kinase CENSG000001051468
STK36 / Q9NRP7 / serine/threonine kinase 36ENSG000001634828


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0031954 positive regulation of protein autophosphorylation IDA
 biological_processGO:0043406 positive regulation of MAP kinase activity IMP
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:1902749 regulation of cell cycle G2/M phase transition IMP
 cellular_componentGO:1902911 protein kinase complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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