ENSMUSG00000042567


Mus musculus

Features
Gene ID: ENSMUSG00000042567
  
Biological name :Nek10
  
Synonyms : Nek10 / Q3UGM2 / Serine/threonine-protein kinase Nek10
  
Possible biological names infered from orthology : NIMA related kinase 10 / Q6ZWH5
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: A1
Gene start: 14803415
Gene end: 15012059
  
Corresponding Affymetrix probe sets: 10412805 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000108249
Ensembl peptide - ENSMUSP00000108250
Ensembl peptide - ENSMUSP00000123151
Ensembl peptide - ENSMUSP00000153142
NCBI entrez gene - 674895     See in Manteia.
MGI - MGI:2685128
RefSeq - XM_006518096
RefSeq - XM_011244771
RefSeq - XM_017316165
RefSeq - NM_001195229
RefSeq - XM_006518092
RefSeq Peptide - NP_001182158
swissprot - Q3UGM2
swissprot - F6XT14
swissprot - K3W4R8
Ensembl - ENSMUSG00000042567
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nek10ENSDARG00000025335Danio rerio
 ENSGALG00000040569Gallus gallus
 ENSGALG00000011322Gallus gallus
 NEK10ENSG00000163491Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Stk36 / Q69ZM6 / serine/threonine kinase 36 / Q9NRP7*ENSMUSG0000003327613
Aurka / P97477 / Aurora kinase A / O14965*ENSMUSG0000002749610
Aurkb / O70126 / Aurora kinase B / Q96GD4*ENSMUSG000000208977
Aurkc / Q9UQB9* / aurora kinase C*ENSMUSG000000708377


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR000719  Protein kinase domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Mthfd1tm2b(KOMP)Wtsi/Mthfd1tm2b(KOMP)Wtsi
Genetic Background: C57BL/6N-Mthfd1tm2b(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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