ENSG00000163517


Homo sapiens

Features
Gene ID: ENSG00000163517
  
Biological name :HDAC11
  
Synonyms : HDAC11 / histone deacetylase 11 / Q96DB2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p25.1
Gene start: 13479724
Gene end: 13506424
  
Corresponding Affymetrix probe sets: 219847_at (Human Genome U133 Plus 2.0 Array)   227679_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384706
Ensembl peptide - ENSP00000384123
Ensembl peptide - ENSP00000385252
Ensembl peptide - ENSP00000429794
Ensembl peptide - ENSP00000412514
Ensembl peptide - ENSP00000411792
Ensembl peptide - ENSP00000402298
Ensembl peptide - ENSP00000401487
Ensembl peptide - ENSP00000399792
Ensembl peptide - ENSP00000398651
Ensembl peptide - ENSP00000396122
Ensembl peptide - ENSP00000395188
Ensembl peptide - ENSP00000385528
Ensembl peptide - ENSP00000385475
Ensembl peptide - ENSP00000295757
Ensembl peptide - ENSP00000384019
NCBI entrez gene - 79885     See in Manteia.
OMIM - 607226
RefSeq - XM_017007234
RefSeq - NM_001136041
RefSeq - NM_024827
RefSeq - XM_005265491
RefSeq - XM_005265492
RefSeq - XM_006713338
RefSeq - XM_011534131
RefSeq - XM_011534132
RefSeq - XM_011534135
RefSeq Peptide - NP_001129513
RefSeq Peptide - NP_001317565
RefSeq Peptide - NP_079103
swissprot - F8WF94
swissprot - Q96DB2
swissprot - A0A024R2I1
swissprot - Q658J9
swissprot - E7ETT9
swissprot - C9JMH0
swissprot - C9JEC8
swissprot - C9JBI4
swissprot - C9J528
swissprot - B5MD06
swissprot - B5MCV5
swissprot - B5MCS3
swissprot - B5MCU6
swissprot - B5MCQ6
swissprot - B5MC52
Ensembl - ENSG00000163517
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hdac11ENSDARG00000087573Danio rerio
 HDAC11ENSGALG00000005092Gallus gallus
 Hdac11ENSMUSG00000034245Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HDAC2 / Q92769 / histone deacetylase 2ENSG0000019659127
HDAC1 / Q13547 / histone deacetylase 1ENSG0000011647827
HDAC8 / Q9BY41 / histone deacetylase 8ENSG0000014709922
HDAC3 / O15379 / histone deacetylase 3ENSG0000017172022


Protein motifs (from Interpro)
Interpro ID Name
 IPR000286  Histone deacetylase family
 IPR023696  Ureohydrolase domain superfamily
 IPR023801  Histone deacetylase domain
 IPR037138  Histone deacetylase domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0014003 oligodendrocyte development IEA
 biological_processGO:0016575 histone deacetylation IDA
 biological_processGO:0070932 histone H3 deacetylation IEA
 cellular_componentGO:0000118 histone deacetylase complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004407 histone deacetylase activity IEA
 molecular_functionGO:0008134 transcription factor binding TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) IEA


Pathways (from Reactome)
Pathway description
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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