ENSG00000163605


Homo sapiens

Features
Gene ID: ENSG00000163605
  
Biological name :PPP4R2
  
Synonyms : PPP4R2 / protein phosphatase 4 regulatory subunit 2 / Q9NY27
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p13
Gene start: 72996785
Gene end: 73069199
  
Corresponding Affymetrix probe sets: 220764_at (Human Genome U133 Plus 2.0 Array)   225519_at (Human Genome U133 Plus 2.0 Array)   226317_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418750
Ensembl peptide - ENSP00000418568
Ensembl peptide - ENSP00000349124
Ensembl peptide - ENSP00000418675
Ensembl peptide - ENSP00000419055
Ensembl peptide - ENSP00000420098
NCBI entrez gene - 151987     See in Manteia.
OMIM - 613822
RefSeq - NM_174907
RefSeq - NM_001318025
RefSeq - NM_001318026
RefSeq - NM_001318027
RefSeq - NM_001318028
RefSeq Peptide - NP_001304954
RefSeq Peptide - NP_777567
RefSeq Peptide - NP_001304957
RefSeq Peptide - NP_001304956
RefSeq Peptide - NP_001304955
swissprot - Q9NY27
swissprot - C9IZ04
swissprot - C9IZF4
swissprot - F8WCA1
swissprot - F8WDK3
swissprot - H7C559
Ensembl - ENSG00000163605
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A1L1M4ENSDARG00000053447Danio rerio
 ppp4r2aENSDARG00000026540Danio rerio
 PPP4R2ENSGALG00000007810Gallus gallus
 Ppp4r2ENSMUSG00000052144Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR015267  Protein phosphatase 4 core regulatory subunit R2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006464 cellular protein modification process TAS
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IMP
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome TAS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0030289 protein phosphatase 4 complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA
 molecular_functionGO:0030674 protein binding, bridging IMP


Pathways (from Reactome)
Pathway description
Processing of DNA double-strand break ends


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000149923 PPP4C / P60510 / protein phosphatase 4 catalytic subunit  / complex
 ENSG00000117748 RPA2 / P15927 / replication protein A2  / reaction
 ENSG00000106399 RPA3 / P35244 / replication protein A3  / reaction
 ENSG00000132383 RPA1 / P27694 / replication protein A1  / reaction






 

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