ENSG00000164398


Homo sapiens

Features
Gene ID: ENSG00000164398
  
Biological name :ACSL6
  
Synonyms : ACSL6 / acyl-CoA synthetase long chain family member 6 / Q9UKU0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q31.1
Gene start: 131949973
Gene end: 132012243
  
Corresponding Affymetrix probe sets: 211207_s_at (Human Genome U133 Plus 2.0 Array)   213683_at (Human Genome U133 Plus 2.0 Array)   216409_at (Human Genome U133 Plus 2.0 Array)   229725_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000368566
Ensembl peptide - ENSP00000442124
Ensembl peptide - ENSP00000413329
Ensembl peptide - ENSP00000398423
Ensembl peptide - ENSP00000398381
Ensembl peptide - ENSP00000397507
Ensembl peptide - ENSP00000394810
Ensembl peptide - ENSP00000389189
Ensembl peptide - ENSP00000388424
Ensembl peptide - ENSP00000296869
Ensembl peptide - ENSP00000349608
Ensembl peptide - ENSP00000368542
Ensembl peptide - ENSP00000368546
Ensembl peptide - ENSP00000368548
Ensembl peptide - ENSP00000368557
NCBI entrez gene - 23305     See in Manteia.
OMIM - 604443
RefSeq - NM_015256
RefSeq - NM_001009185
RefSeq - NM_001205247
RefSeq - NM_001205248
RefSeq - NM_001205250
RefSeq - NM_001205251
RefSeq Peptide - NP_001009185
RefSeq Peptide - NP_001192176
RefSeq Peptide - NP_001192177
RefSeq Peptide - NP_001192179
RefSeq Peptide - NP_001192180
RefSeq Peptide - NP_056071
swissprot - Q9UKU0
swissprot - C9JT10
swissprot - C9JPA5
swissprot - C9JK59
swissprot - C9J8C7
swissprot - C9J4I1
swissprot - C9J3Z0
swissprot - E7ERD7
Ensembl - ENSG00000164398
  
Related genetic diseases (OMIM): 604443 - Myelodysplastic syndrome
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO018363.1ENSDARG00000099648Danio rerio
 LO018363.2ENSDARG00000113657Danio rerio
 ENSGALG00000006644Gallus gallus
 Acsl6ENSMUSG00000020333Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC026398.1ENSG0000028193889
ACSL1 / P33121 / acyl-CoA synthetase long chain family member 1ENSG0000015172665
ACSL5 / Q9ULC5 / acyl-CoA synthetase long chain family member 5ENSG0000019714259
ACSL4 / O60488 / acyl-CoA synthetase long chain family member 4ENSG0000006836630
ACSL3 / O95573 / acyl-CoA synthetase long chain family member 3ENSG0000012398330
ACSBG1 / Q96GR2 / acyl-CoA synthetase bubblegum family member 1ENSG0000010374022
ACSBG2 / Q5FVE4 / acyl-CoA synthetase bubblegum family member 2ENSG0000013037720


Protein motifs (from Interpro)
Interpro ID Name
 IPR000873  AMP-dependent synthetase/ligase
 IPR020845  AMP-binding, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001676 long-chain fatty acid metabolic process IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006637 acyl-CoA metabolic process NAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0035338 long-chain fatty-acyl-CoA biosynthetic process TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005778 peroxisomal membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004467 long-chain fatty acid-CoA ligase activity TAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0102391 decanoate-CoA ligase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of very long-chain fatty acyl-CoAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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