ENSG00000167491


Homo sapiens

Features
Gene ID: ENSG00000167491
  
Biological name :GATAD2A
  
Synonyms : GATAD2A / GATA zinc finger domain containing 2A / Q86YP4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.11
Gene start: 19385826
Gene end: 19508931
  
Corresponding Affymetrix probe sets: 218131_s_at (Human Genome U133 Plus 2.0 Array)   222526_at (Human Genome U133 Plus 2.0 Array)   229166_s_at (Human Genome U133 Plus 2.0 Array)   234294_x_at (Human Genome U133 Plus 2.0 Array)   236932_s_at (Human Genome U133 Plus 2.0 Array)   238324_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000390495
Ensembl peptide - ENSP00000384899
Ensembl peptide - ENSP00000403703
Ensembl peptide - ENSP00000477171
Ensembl peptide - ENSP00000476500
Ensembl peptide - ENSP00000414252
Ensembl peptide - ENSP00000411869
Ensembl peptide - ENSP00000407293
Ensembl peptide - ENSP00000404212
Ensembl peptide - ENSP00000351552
Ensembl peptide - ENSP00000353463
NCBI entrez gene - 54815     See in Manteia.
OMIM - 614997
RefSeq - XM_017026911
RefSeq - NM_001300946
RefSeq - NM_017660
RefSeq - XM_011528105
RefSeq - XM_017026901
RefSeq - XM_017026902
RefSeq - XM_017026903
RefSeq - XM_017026904
RefSeq - XM_017026905
RefSeq - XM_017026906
RefSeq - XM_017026907
RefSeq - XM_017026908
RefSeq - XM_017026909
RefSeq - XM_017026910
RefSeq Peptide - NP_001287875
RefSeq Peptide - NP_060130
swissprot - C9JJK9
swissprot - C9JHD7
swissprot - C9JGN4
swissprot - A0A024R7M6
swissprot - H7C3H1
swissprot - V9GYX5
swissprot - A0A024R7K7
swissprot - Q86YP4
swissprot - C9JVY3
swissprot - V9GY85
swissprot - C9JMI3
Ensembl - ENSG00000167491
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gatad2abENSDARG00000006192Danio rerio
 GATAD2AENSGALG00000042900Gallus gallus
 Q8CHY6ENSMUSG00000036180Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WXI9 / GATAD2B / GATA zinc finger domain containing 2BENSG0000014361442


Protein motifs (from Interpro)
Interpro ID Name
 IPR000679  Zinc finger, GATA-type
 IPR013088  Zinc finger, NHR/GATA-type
 IPR032346  Transcriptional repressor p66, coiled-coil MBD2-interaction domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006306 DNA methylation TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0016581 NuRD complex IDA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0030674 protein binding, bridging IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HDACs deacetylate histones
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Regulation of TP53 Activity through Acetylation
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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