ENSG00000167759


Homo sapiens

Features
Gene ID: ENSG00000167759
  
Biological name :KLK13
  
Synonyms : kallikrein related peptidase 13 / KLK13 / Q9UKR3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.41
Gene start: 51056206
Gene end: 51065114
  
Corresponding Affymetrix probe sets: 205783_at (Human Genome U133 Plus 2.0 Array)   216670_at (Human Genome U133 Plus 2.0 Array)   217315_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000470931
Ensembl peptide - ENSP00000472596
Ensembl peptide - ENSP00000472248
Ensembl peptide - ENSP00000156476
Ensembl peptide - ENSP00000334079
Ensembl peptide - ENSP00000365995
Ensembl peptide - ENSP00000392640
Ensembl peptide - ENSP00000470245
Ensembl peptide - ENSP00000470555
NCBI entrez gene - 26085     See in Manteia.
OMIM - 605505
RefSeq - NM_015596
RefSeq Peptide - NP_056411
swissprot - Q5BQ97
swissprot - Q5BQ99
swissprot - Q86VI7
swissprot - A0A1R3UCE9
swissprot - Q9UKR3
swissprot - M0R218
swissprot - Q5BQ95
Ensembl - ENSG00000167759
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Klk13ENSMUSG00000054046Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLK11 / Q9UBX7 / kallikrein related peptidase 11ENSG0000016775745
KLK14 / Q9P0G3 / kallikrein related peptidase 14ENSG0000012943744
KLK8 / O60259 / kallikrein related peptidase 8ENSG0000012945544
KLK6 / Q92876 / kallikrein related peptidase 6ENSG0000016775543
KLK15 / Q9H2R5 / kallikrein related peptidase 15ENSG0000017456242
KLK9 / Q9UKQ9 / kallikrein related peptidase 9ENSG0000021302240
AC011473.4ENSG0000026974140
PRSS2 / P07478 / serine protease 2ENSG0000027589639
PRSS1 / P07477 / serine protease 1ENSG0000020498338
PRSS3 / P35030 / serine protease 3ENSG0000001043838


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016485 protein processing IEA
 biological_processGO:0070268 cornification TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0030141 secretory granule IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004175 endopeptidase activity IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000178172 Q6UWN8 / SPINK6 / serine peptidase inhibitor, Kazal type 6  / complex / reaction






 

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