ENSG00000129437


Homo sapiens

Features
Gene ID: ENSG00000129437
  
Biological name :KLK14
  
Synonyms : kallikrein related peptidase 14 / KLK14 / Q9P0G3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.41
Gene start: 51077495
Gene end: 51084245
  
Corresponding Affymetrix probe sets: 220573_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000375678
Ensembl peptide - ENSP00000156499
NCBI entrez gene - 43847     See in Manteia.
OMIM - 606135
RefSeq - XM_017026820
RefSeq - NM_001311182
RefSeq - NM_022046
RefSeq Peptide - NP_001298111
RefSeq Peptide - NP_071329
swissprot - Q9P0G3
swissprot - A0A024R4M6
Ensembl - ENSG00000129437
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Klk14ENSMUSG00000044737Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLK8 / O60259 / kallikrein related peptidase 8ENSG0000012945548
KLK13 / Q9UKR3 / kallikrein related peptidase 13ENSG0000016775946
KLK11 / Q9UBX7 / kallikrein related peptidase 11ENSG0000016775744
KLK15 / Q9H2R5 / kallikrein related peptidase 15ENSG0000017456243
KLK9 / Q9UKQ9 / kallikrein related peptidase 9ENSG0000021302242
AC011473.4ENSG0000026974142
KLK6 / Q92876 / kallikrein related peptidase 6ENSG0000016775542
PRSS2 / P07478 / serine protease 2ENSG0000027589639
PRSS3 / P35030 / serine protease 3ENSG0000001043839
PRSS1 / P07477 / serine protease 1ENSG0000020498339


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IDA
 biological_processGO:0009566 fertilization IDA
 biological_processGO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway IDA
 biological_processGO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway IDA
 biological_processGO:0048730 epidermis morphogenesis IDA
 biological_processGO:0070268 cornification TAS
 biological_processGO:0070684 seminal clot liquefaction IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004252 serine-type endopeptidase activity NAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000178172 Q6UWN8 / SPINK6 / serine peptidase inhibitor, Kazal type 6  / complex / reaction






 

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