ENSG00000168619


Homo sapiens

Features
Gene ID: ENSG00000168619
  
Biological name :ADAM18
  
Synonyms : ADAM18 / ADAM metallopeptidase domain 18 / Q9Y3Q7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p11.22
Gene start: 39584489
Gene end: 39730064
  
Corresponding Affymetrix probe sets: 1568970_at (Human Genome U133 Plus 2.0 Array)   207597_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000428083
Ensembl peptide - ENSP00000429908
Ensembl peptide - ENSP00000429335
Ensembl peptide - ENSP00000265707
Ensembl peptide - ENSP00000369195
NCBI entrez gene - 8749     See in Manteia.
RefSeq - NM_001190956
RefSeq - NM_001320313
RefSeq - NM_014237
RefSeq Peptide - NP_001307242
RefSeq Peptide - NP_055052
RefSeq Peptide - NP_001177885
swissprot - Q9Y3Q7
swissprot - E5RIP0
swissprot - E5RK96
Ensembl - ENSG00000168619
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:174164ENSDARG00000057138Danio rerio
 ENSGALG00000044168Gallus gallus
 ENSGALG00000044866Gallus gallus
 Adam18ENSMUSG00000031552Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADAM32 / Q8TC27 / ADAM metallopeptidase domain 32ENSG0000019714041
ADAM2 / Q99965 / ADAM metallopeptidase domain 2ENSG0000010475540
ADAM9 / Q13443 / ADAM metallopeptidase domain 9ENSG0000016861532
ADAM21 / Q9UKJ8 / ADAM metallopeptidase domain 21ENSG0000013998527
ADAM30 / Q9UKF2 / ADAM metallopeptidase domain 30ENSG0000013424927
ADAM29 / Q9UKF5 / ADAM metallopeptidase domain 29ENSG0000016859426
ADAM20 / O43506 / ADAM metallopeptidase domain 20ENSG0000013400725


Protein motifs (from Interpro)
Interpro ID Name
 IPR001590  Peptidase M12B, ADAM/reprolysin
 IPR001762  Disintegrin domain
 IPR002870  Peptidase M12B, propeptide
 IPR006586  ADAM, cysteine-rich
 IPR018358  Disintegrin, conserved site
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR034027  Reprolysin domain, adamalysin-type
 IPR036436  Disintegrin domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis TAS
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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